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Discovery and optimization of dihydropteridone derivatives as novel PLK1 and BRD4 dual inhibitor for the treatment of cancer.

Bioorg Med Chem 101: 0-0 (2024)

Shenyang Pharmaceutical University

2D SDF 3D SDF TSV

Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for drug design.

Bioorg Med Chem 101: 0-0 (2024)

Bristol Myers Squibb

2D SDF 3D SDF TSV

Synthesis, biological evaluation, and stability studies of raloxifene mono- and bis-sulfamates as dual-targeting agents.

Bioorg Med Chem 101: 0-0 (2024)

University of Sharjah

2D SDF 3D SDF TSV

Research progress of LSD1-based dual-target agents for cancer therapy.

Bioorg Med Chem 101: 0-0 (2024)

Xinxiang University

2D SDF 3D SDF TSV

Multi-target potential of newly designed tacrine-derived cholinesterase inhibitors: Synthesis, computational and pharmacological study.

Bioorg Med Chem 101: 0-0 (2024)

University of Belgrade-Institute of Chemistry

2D SDF 3D SDF TSV