Compile Data Set for Download or QSAR
Report error Found 92 of affinity data for UniProtKB/TrEMBL: V5TFZ2
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601687(CHEMBL5192551)
Affinity DataKd:  9.10E+3nMAssay Description:Binding affinity to full length His-tagged DENV-2 NS5 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to DENV3 NT-647-NHS labeled NS5 RdRp after 1 hr by microscale thermophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525241(CHEMBL4449109)
Affinity DataEC50:  4.90E+3nMAssay Description:Inhibition of His-tagged DENV2 NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525241(CHEMBL4449109)
Affinity DataEC50:  13nMAssay Description:Inhibition of His-tagged DENV2 NS5 RNA dependent RNA polymerase expressed in baculovirus infected sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464490(CHEMBL4282493)
Affinity DataIC50: 16nMAssay Description:Inhibition of DENV3 full length NS5 RdRp assessed as decrease in dsRNA levels preincubated for 20 mins followed by ss-RNA and ATTO-CTP, ATP, GTP and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 41nMAssay Description:Inhibition of Dengue virus ribose 2'-O methyltransferase using RNA substrate after 20 mins in presence of [methyl-3H]-AdoMet by microbeta counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323197(sotetsuflavone | 7''-O-methylamentoflavone | CHEMB...)
Affinity DataIC50: 160nMAssay Description:Inhibition of DENV NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323197(sotetsuflavone | 7''-O-methylamentoflavone | CHEMB...)
Affinity DataIC50: 160nMAssay Description:Inhibition of DENV C-terminal histidine-tagged NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323214(CHEMBL291426 | 6-[4-(5,7-Dihydroxy-4-oxo-4H-chrome...)
Affinity DataIC50: 260nMAssay Description:Inhibition of DENV C-terminal histidine-tagged NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323212(CHEMBL63677 | 6-[5-(5,7-Dihydroxy-4-oxo-4H-chromen...)
Affinity DataIC50: 330nMAssay Description:Inhibition of DENV C-terminal histidine-tagged NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50274119(CHEMBL4126343)
Affinity DataIC50: 340nMAssay Description:Inhibition of Dengue virus 4 NS5 full length RdRp activity using RNA as template assessed as inhibition of NTPs incorporation after 90 mins by FAPA a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50274120(CHEMBL3417270)
Affinity DataIC50: 360nMAssay Description:Inhibition of Dengue virus 2 NS5 full length RdRp activity using RNA as template/primer assessed as inhibition of [alpha3P]GTP incorporation by SDS-P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Dengue virus ribose 2'-O methyltransferase using RNA substrate after 20 mins in presence of [methyl-3H]-AdoMet by microbeta counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464499(CHEMBL4288319)
Affinity DataIC50: 600nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50274124(CHEMBL4125966 | US10793591, Compound 12)
Affinity DataIC50: 650nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50323198(4'''-methylamentoflavone | podocarpusflavone A | C...)
Affinity DataIC50: 750nMAssay Description:Inhibition of DENV NS5/RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464494(CHEMBL4292407)
Affinity DataIC50: 900nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525250(CHEMBL4526128)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged DENV3 NS5 RNA dependent RNA polymerase (272 to 900 residues) after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50274121(CHEMBL4127092)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50362887(AVICULARIN)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of DENV/NS5 RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of DENV/NS5 RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dengue virus NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464502(CHEMBL4281417)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dengue virus NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50362884(CHEMBL402947 | Spiraeoside (5))
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DENV/NS5 RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50274122(CHEMBL4127819)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601687(CHEMBL5192551)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of full length His-tagged DENV-2 NS5 incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DENV/NS5 RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50217942(3-Rhamnoglucosylquercetin | cid_5280805 | CHEMBL22...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DENV/NS5 RNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50601688(CHEMBL5199491)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of full length His-tagged DENV-2 NS5 incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525251(CHEBI:90290 | CHEMBL1418094)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DENV3 2'-O-methyltransferase using m7G*pppA-RNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525251(CHEBI:90290 | CHEMBL1418094)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DENV2 2'-O-methyltransferase using m7G*pppA-RNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464498(CHEMBL4279581)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50274125(CHEMBL4127565)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464511(CHEMBL4289289)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300193(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of DENV-2 NS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464508(CHEMBL4284511)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464495(CHEMBL4281097)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50525249(CHEMBL4587069)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged DENV2 NGC NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300193(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of DENV-4 NS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464512(CHEMBL4284513)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50274118(CHEMBL4127030 | US10793591, Compound 7a)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464489(CHEMBL4281094)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464506(CHEMBL4280007)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464491(CHEMBL4295172)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464507(CHEMBL4289005)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464496(CHEMBL4291308)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464505(CHEMBL3233235)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Dengue virus)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50464501(CHEMBL3233241)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of DENV3 NS5 RdRp using ss-RNA PolyC as template and GTP as substrate assessed as decrease in dsRNA levels after 1 hr by PicoGreen-based f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 92 total ) | Next | Last >>
Jump to: