Affinity DataEC50: 0.0120nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0440nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0410nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00900nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0260nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0330nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0110nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0750nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 6.91E+3nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00600nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0530nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0280nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0340nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0190nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0140nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Inverse agonist activity at TLX (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.00300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00300nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00400nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0130nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00800nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0140nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00800nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00700nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 7.31E+3nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00500nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00800nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.00900nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0120nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0120nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0150nMAssay Description:Assays were performed according to the manufacturer's protocol (PerkinElmer, USA), with the following modifications: Ligands were tested for TLX-...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human Gal4-fused TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP16 assessed as repressor activity of receptor by me...More data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to TLX LBD expressed in His6-tagged Escherichia coli Rosetta assessed as binding constant measured after 300 sec at 200 mM by isothe...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
Affinity DataEC50: 4.30E+4nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+4nMAssay Description:Agonist activity at full length TLX activating element expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as dec...More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair
