Compile Data Set for Download or QSAR
Report error Found 47 of affinity data for UniProtKB/TrEMBL: Q9Y2U9
TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50644835(CHEMBL5566038)
Affinity DataKd:  360nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743572(US20250163075, Example 15A)
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743570(US20250163075, Example 23)
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743574(US20250163075, Example 24)
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743573(US20250163075, Example 19)
Affinity DataIC50: 1.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743569(US20250163075, Example 14)
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743568(US20250163075, Example 13)
Affinity DataIC50: 1.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743571(US20250163075, Example 27)
Affinity DataIC50: 3.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743563(US20250163075, Example 8)
Affinity DataIC50: 3.90E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708889(2-(1-methyl-10-oxo-4-(1- (pyridin-2-ylmethyl)azeti...)
Affinity DataIC50: 4.60E+3nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743566(US20250163075, Example 11)
Affinity DataIC50: 7.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708903(2-(9-oxo-2-(3-phenylpropan- oyl)-7-oxa-2,10-diazas...)
Affinity DataIC50: 8.20E+3nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743567(US20250163075, Example 12)
Affinity DataIC50: 8.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743565(US20250163075, Example 10)
Affinity DataIC50: 9.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708892(2-(4-(acetyl-D-prolyl)-1- methyl-10-oxo-1,4,9- tri...)
Affinity DataIC50: 1.25E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708883(2-(4-(2-(4-hydroxyphen- yl)propanoyl)-1-methyl- 10...)
Affinity DataIC50: 1.98E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743564(US20250163075, Example 9)
Affinity DataIC50: 2.03E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708897(US20240425519, Compound AC0978)
Affinity DataIC50: 2.21E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM743562(US20250163075, Example i)
Affinity DataIC50: 2.41E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708872(2-(1-methyl-10-oxo-4-(2- phenylcyclopropane-1- car...)
Affinity DataIC50: 3.20E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708880(2-(1-methyl-10-oxo-4- (phenylcarbamoyl)-1,4,9- tri...)
Affinity DataIC50: 3.36E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708899(2-(9-oxo-2-((R)-2-phenylpro- panoyl)-7-oxa-2,10-di...)
Affinity DataIC50: 3.96E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708900(2-(2-(cyclopentanecarbonyl)- 9-oxo-7-oxa-2,10-diaz...)
Affinity DataIC50: 4.01E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708891(2-(4-(benzoyl-D-prolyl)- 1-methyl-10-oxo-1,4,9- tr...)
Affinity DataIC50: 4.54E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708881(2-(4-(benzylcarbamoyl)- 1-methyl-10-oxo-1,4,9- tri...)
Affinity DataIC50: 4.59E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708902(2-(2-(2-(3-hydroxypyrrolidin- 1-yl)pyrimidin-4-yl)...)
Affinity DataIC50: 4.75E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708896(2-(9-oxo-2-(2-phenylpropano- yl)-7-oxa-2,10-diazas...)
Affinity DataIC50: 5.00E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708901(2-(2-(cyclobutanecarbonyl)-9- oxo-7-oxa-2,10-diaza...)
Affinity DataIC50: 5.10E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708873(2-(1-methyl-4-(2-methyl- 3-phenylpropanoyl)-10- ox...)
Affinity DataIC50: 5.64E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708898(US20240425519, Compound AC0979)
Affinity DataIC50: 6.37E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708887(2-(4-(1-benzyl-5-oxo- pyrrolidine-3-carbonyl)- 1-m...)
Affinity DataIC50: 6.59E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708879(2-(4-(cyclobutylcarbam- oyl)-1-methyl-10-oxo- 1,4,...)
Affinity DataIC50: 9.17E+4nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708882(2-(4-(cyclopropanecar- bonyl)-1-methyl-10-oxo- 1,4...)
Affinity DataIC50: 1.00E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708878(2-(4-(1-hydroxycyclopen- tane-1-carbonyl)-1-meth- ...)
Affinity DataIC50: 1.16E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708895(2-(9-(carboxymethyl)-1-meth- yl-10-oxo-1,4,9-triaz...)
Affinity DataIC50: 1.23E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708884(2-(4-(2-methoxy-2-phen- ylpropanoyl)-1-methyl- 10-...)
Affinity DataIC50: 1.31E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708885(2-(1-methyl-10-oxo-4-(1- phenyl-1H-pyrazole-4- car...)
Affinity DataIC50: 1.48E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708888(2-(4-(1-acetylpiperidine- 4-carbonyl)-1-methyl-10-...)
Affinity DataIC50: 1.91E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708890(2-(4-(1-benzoylazetidine- 3-carbonyl)-1-methyl-10-...)
Affinity DataIC50: 1.99E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708876(2-(1-methyl-4-(2-methyl- 2-phenoxypropanoyl)-10- o...)
Affinity DataIC50: 2.02E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708874(2-(4-(3,3-difluorocyclo- butane-1-carbonyl)-1- met...)
Affinity DataIC50: 2.95E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708875(2-(4-(1-(4-fluorophenyl)- cyclopropane-1-carbon- y...)
Affinity DataIC50: 3.48E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708894(2-(4-(2-amino-5-chloro-6- methylpyrimidin-4-yl)-1-...)
Affinity DataIC50: 3.89E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708893(2-(4-(6-acetyl-5,6,7,8-tetra- hydropyrido[4,3-d]py...)
Affinity DataIC50: 4.45E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708877(2-(4-((1,3-trans)-3-((tert- butoxycarbonyl)amino)-...)
Affinity DataIC50: 4.93E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708886(2-(4-((S)-1-(tert-butoxy- carbonyl)azetidine-2- ca...)
Affinity DataIC50: 4.96E+5nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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TargetKelch domain-containing protein 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM708904(2-(2-(2-methylpyrimidin-4-yl)- 9-oxo-7-oxa-2,10-di...)
Affinity DataIC50: 1.39E+6nMAssay Description:The following is a description of an assay for evaluating ligand binding to KLHDC2.Amplified Luminescence Proximity Homogenous Assay (AlphaScreen) wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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