Compile Data Set for Download or QSAR
Report error Found 85 for UniProtKB: Q9Y2C9
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50399456(CHEMBL2179399)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589247(CHEMBL5196081)
Affinity DataEC50:  5.64E+3nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589248(CHEMBL5189797)
Affinity DataEC50:  5.87E+3nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589249(CHEMBL5207928)
Affinity DataEC50:  4.27E+3nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589250(CHEMBL5172445)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589251(CHEMBL5195703)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589252(CHEMBL5192180)
Affinity DataEC50:  134nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589253(CHEMBL5178934)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589254(CHEMBL5206630)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50589255(CHEMBL5203798)
Affinity DataEC50:  252nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTLR2/TLR6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50399457(CHEMBL2179400)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human TLR2/TLR6 expressed in HEK-Blue hTLR2-TLR6 cells by SEAP reporter gene based Quanti-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649763(8-fluoro-4-hydroxy-3-(2- methoxyethyl)-6-(3-(4- (p...)
Affinity DataIC50: 200nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649759(2-fluoro-6-formyl-4-(3-(4- (pyrrolidin-1-yl)phenyl...)
Affinity DataIC50: 300nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649710(3-fluoro-5-formyl-4-hydroxy- N-(6-(pyrrolidin-1-yl...)
Affinity DataIC50: 300nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649747((3-fluoro-4-hydroxy-5-(((4- methylpiperazin-1- yl)...)
Affinity DataIC50: 400nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649723(5-hydroxy-2-(2-(6-(pyrrolidin- 1-yl)pyridin-3-yl)t...)
Affinity DataIC50: 400nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649711(3-fluoro-2-hydroxy-5-(4-(4- (pyrrolidin-1- yl)phen...)
Affinity DataIC50: 400nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649762(8-fluoro-4-hydroxy-3-methyl- 6-(3-(4-(pyrrolidin-1...)
Affinity DataIC50: 430nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649757(2-fluoro-6-formyl-4-(3-(4- (pyrrolidin-1-yl)phenyl...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649748((3-fluoro-4-hydroxy-5- ((morpholinoimino)methyl) p...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649697(3-fluoro-5-formyl-4-hydroxy- N-(5-phenylthiazol-2-...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649721(3-fluoro-2-hydroxy-5-(1-(4- (trifluoromethyl)pheny...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649756(2-fluoro-6-formyl-4-(3-(4- (pyrrolidin-1-yl)phenyl...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649758(2-fluoro-6-formyl-4-(3-(4- (pyrrolidin-1-yl)phenyl...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649719(3-fluoro-5-formyl-4-hydroxy- N-(5-(4- (trifluorome...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649760(2-fluoro-6-formyl-4-(3-(4- (pyrrolidin-1-yl)phenyl...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649751(3-fluoro-5-formyl-4-hydroxy- N-(3-(4-(pyrrolidin-1...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649705(3-fluoro-5-formyl-4-hydroxy- N-(5-(3-(pyrrolidin-1...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649761(2-(2-fluoro-6-formyl-4-(3-(4- (pyrrolidin-1-yl)phe...)
Affinity DataIC50: 600nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649704(3-fluoro-N-(5-(4- fluorophenyl)thiazol-2-yl)-5- fo...)
Affinity DataIC50: 700nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649724(3-fluoro-2-hydroxy-5-(3-(6- (pyrrolidin-1-yl)pyrid...)
Affinity DataIC50: 800nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649722(2-hydroxy-3-methoxy-5-(1-(4- (trifluoromethyl)phen...)
Affinity DataIC50: 800nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649708(3-fluoro-5-formyl-4-hydroxy- N-(2-phenyloxazol-4- ...)
Affinity DataIC50: 900nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649703(N-(3-fluoro-5-formyl-4- hydroxyphenyl)-5- phenylth...)
Affinity DataIC50: 900nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649749((E)-2-fluoro-6-(((4- methylpiperazin-1- yl)imino)m...)
Affinity DataIC50: 900nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649706(3-fluoro-5-formyl-4-hydroxy- N-(5-(4-(pyrrolidin-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649750(2-fluoro-6- ((morpholinoimino)methyl)-4- (3-(4-(py...)
Affinity DataIC50: 1.00E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649755((Z)-3-fluoro-2-hydroxy-5-(3- (4-(pyrrolidin-1-yl)p...)
Affinity DataIC50: 1.03E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649738(relative-(S)-3-fluoro-2- hydroxy-5-(2-(4-(pyrrolid...)
Affinity DataIC50: 1.30E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649739(relative-(R)-3-fluoro-2- hydroxy-5-(2-(4-(pyrrolid...)
Affinity DataIC50: 1.30E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649753(5-(3-(4-(3,3-difluoroazetidin- 1-yl)phenyl)-1,2,4-...)
Affinity DataIC50: 1.30E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649732(rac-3-fluoro-2-hydroxy-5-(2- (4-(pyrrolidin-1- yl)...)
Affinity DataIC50: 1.60E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649696(3-fluoro-5-formyl-4-hydroxy- N-(5-(piperidin-1-yl)...)
Affinity DataIC50: 1.70E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649734(relative-(R)-3-fluoro-2- hydroxy-5-(2-(4-(pyrrolid...)
Affinity DataIC50: 1.74E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649733(relative-(S)-3-fluoro-2- hydroxy-5-(2-(4-(pyrrolid...)
Affinity DataIC50: 1.88E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649742(relative-(S)-3-fluoro-2- hydroxy-5-(3-(4-(pyrrolid...)
Affinity DataIC50: 2.20E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649695(3-fluoro-5-formyl-4-hydroxy- N-(5-phenyl-1,3,4-thi...)
Affinity DataIC50: 2.20E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649743(3-fluoro-5-formyl-4-hydroxy- N-methyl-N-(3- phenyl...)
Affinity DataIC50: 2.25E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649698(N-(5-(4-cyclopropylpiperazin- 1-yl)thiazol-2-yl)-3...)
Affinity DataIC50: 2.70E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM649735(rac-3-fluoro-2-hydroxy-5-(2- (3-(pyrrolidin-1- yl)...)
Affinity DataIC50: 3.10E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

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