Compile Data Set for Download or QSAR
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TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199225(US9216998, 8)
Affinity DataIC50: 4nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
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TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443626(CHEMBL3092451)
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443627(CHEMBL3092450 | US9216998, 5)
Affinity DataIC50: 17nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
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TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443627(CHEMBL3092450 | US9216998, 5)
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 26nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
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TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)
Affinity DataIC50: 31nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)
Affinity DataIC50: 31nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443625(CHEMBL3092448 | US9216998, 25)
Affinity DataIC50: 31nMAssay Description:Inhibition of endothelial lipase in mouse cells after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199205(US9216998, 9)
Affinity DataIC50: 36nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
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TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 48nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199226(US9216998, 10)
Affinity DataIC50: 75nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199207(US9216998, 19)
Affinity DataIC50: 87nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
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TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50522804(CHEMBL4437751)
Affinity DataIC50: 94nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199221(US9216998, 3)
Affinity DataIC50: 96nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50458640(CHEMBL4203934)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant mouse endothelial lipase expressed in HEK293F cells using HDL as substrate pretreated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50522808(CHEMBL4520847)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199229(US9216998, 27)
Affinity DataIC50: 108nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50: 120nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199209(US9216998, 13)
Affinity DataIC50: 124nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199208(US9216998, 12)
Affinity DataIC50: 131nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199223(US9216998, 6)
Affinity DataIC50: 136nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199216(US9216998, 22)
Affinity DataIC50: 142nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199210(US9216998, 14)
Affinity DataIC50: 162nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM151238(US8987314, B34)
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199220(US9216998, 1)
Affinity DataIC50: 195nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM151212(US8987314, B3)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50506505(CHEMBL4460376)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50506498(CHEMBL4581886)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50506506(CHEMBL4465833)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50506504(CHEMBL4460663)
Affinity DataIC50: 200nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199222(US9216998, 4)
Affinity DataIC50: 205nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199215(US9216998, 21)
Affinity DataIC50: 237nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM319015(US10173991, Example 57 | N-[(cyclopropyl- carbamoy...)
Affinity DataIC50: 290nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50: 310nMAssay Description:Inhibition of endothelial lipase in hepatic lipase knock-out mouse plasma using D31-POPC-HDL as substrate incubated for 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM151303(US8987314, B101)
Affinity DataIC50: 320nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199218(US9216998, 24)
Affinity DataIC50: 340nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199217(US9216998, 23)
Affinity DataIC50: 346nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50433475(CHEMBL2381067)
Affinity DataIC50: 470nMAssay Description:Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199214(US9216998, 20)
Affinity DataIC50: 479nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM319014(US10173991, Example 56 | N-[(cyclopropyl- carbamoy...)
Affinity DataIC50: 600nMAssay Description:Inhibition of mouse endothelial lipase expressed in HEK293F cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of mouse plasma by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199228(US9216998, 26)
Affinity DataIC50: 618nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199206(US9216998, 15)
Affinity DataIC50: 677nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50433472(CHEMBL2381069)
Affinity DataIC50: 680nMAssay Description:Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199211(US9216998, 16)
Affinity DataIC50: 1.00E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199227(US9216998, 11)
Affinity DataIC50: 1.20E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199213(US9216998, 18)
Affinity DataIC50: 1.89E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199212(US9216998, 17)
Affinity DataIC50: 3.62E+3nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50522805(CHEMBL4514272)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of hepatic lipase in endothelial lipase knock-out mouse plasma using D31-POPC-HDL as substrate incubated for 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50433474(CHEMBL2381068)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443624(CHEMBL3092449 | US9216998, 28)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
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