Compile Data Set for Download or QSAR
Report error Found 18 of affinity data for UniProtKB/TrEMBL: Q9WJQ1
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 25nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 89nMAssay Description:The HIV-1 RTwt inhibition assay was implemented using the template/primer hybrid poly(A)9oligo(dT)15, digoxigenin- and biotin-labeled nucleotides, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 580nMAssay Description:The HIV-1 RTwt inhibition assay was implemented using the template/primer hybrid poly(A)9oligo(dT)15, digoxigenin- and biotin-labeled nucleotides, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 4.30E+3nMT: 2°CAssay Description:The NNRTI compound to be evaluated (NVP) was serially diluted in 50% DMSO. The reaction mixtures containing 150 nM labeled primer−template hybr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2017
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175341(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 5.42E+3nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175333(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 8.12E+3nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175343(Ethyl4-((1-(4-chlorophenyl)-2-(3,4-dihydroquinolin...)
Affinity DataIC50: 1.23E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175340(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 1.49E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 1.60E+4nMT: 2°CAssay Description:The NNRTI compound to be evaluated (NVP) was serially diluted in 50% DMSO. The reaction mixtures containing 150 nM labeled primer−template hybr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2017
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175339(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 2.38E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175332(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 3.70E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175342(Ethyl 2-((1-(4-chlorophenyl)-2-(3,4-dihydroquinoli...)
Affinity DataIC50: 3.90E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175338(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 4.86E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175334(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 6.83E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175337(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 7.21E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175335(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 8.36E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM175336(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Affinity DataIC50: 9.03E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Birla Institute of Technology

LigandPNGBDBM163696(4-(3-(3,5-Dimethylbenzoyl)pyridin-2-yloxy)benzonit...)
Affinity DataIC50: 1.50E+5nMAssay Description:The HIV-1 RTwt inhibition assay was implemented using the template/primer hybrid poly(A)9oligo(dT)15, digoxigenin- and biotin-labeled nucleotides, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed