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Report error Found 6 of affinity data for UniProtKB/TrEMBL: Q9UPS6
TargetHistone-lysine N-methyltransferase SETD1B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  45nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50524882(CHEMBL4465202)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of C-terminal GST-tagged human SET1B (1629 to 1923 amino acids) expressed in Escherichia coli using core histone as substrate in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50508569(CHEMBL4557353)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SETD1B (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed