Compile Data Set for Download or QSAR
Report error Found 958 for UniProtKB: Q9ULV8
TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710620((S)-2-(3-(cyclobutyl(hydroxy)(4-methyl-4H- 1,2,4-t...)
Affinity DataKd:  29nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710657(2-(6-(ethylamino)-4-(6-(4-methyl-4H-1,2,4- triazol...)
Affinity DataKd:  5.70nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710658(2-(6-(cyclopentylamino)-4-((1s,3s)-3- methoxy-1-(4...)
Affinity DataKd:  23nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710659(2-(6-(cyclopentylamino)-4-((1r,3r)-3- methoxy-1-(4...)
Affinity DataKd:  220nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710662(6-(((S)-2-isopropyl-4-methylpiperazin-1- yl)methyl...)
Affinity DataKd:  12nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710663(6-(((S)-2-isorpopyl-4-methylpiperazin-1- yl)methyl...)
Affinity DataKd:  490nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710664(6-(((S)-2-isopropyl-4-methylpiperazin-1- yl)methyl...)
Affinity DataKd:  5.50E+3nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710665(6-(((S)-2-isopropyl-4-methylpiperazin-1- yl)methyl...)
Affinity DataKd:  1.10E+4nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710666(2-(6-cyclopropyl-4-(3,3-difluoro-1-(4- methyl-4H-1...)
Affinity DataKd:  0.340nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710667(2-(4-(3,3-difluoro-1-(4-methyl-4H-1,2,4- triazol-3...)
Affinity DataKd:  1.10nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710668(2-(3-(1-(4-methyl-4H-1,2,4-triazol-3-yl)-3- methyl...)
Affinity DataKd:  5.60nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710669(2-(3-(1-(4-methyl-4H-1,2,4-triazol-3-yl)-3- oxocyc...)
Affinity DataKd:  200nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710670(2-(3-((1r,3r)-3-hydroxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataKd:  350nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710671(2-(3-((1s,3s)-3-hydroxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataKd:  22nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
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Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710672(2-(3-((1s,3s)-3-methoxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataKd:  67nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710673(2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataKd:  36nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710674((1r,3r)-3-(4-methyl-4H-1,2,4-triazol-3-yl)-3- (3-(...)
Affinity DataKd:  15nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710675((1s,3s)-3-(4-methyl-4H-1,2,4-triazol-3-yl)- 3-(3-(...)
Affinity DataKd:  22nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710676(2-(3-((1s,3s)-3-hydroxy-3-methyl-1-(4- methyl-4H-1...)
Affinity DataKd:  90nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710677((2-(3-((1r,3r)-3-hydroxy-3-methyl-1-(4- methyl-4H-...)
Affinity DataKd:  430nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710678(2-(3-((1r,3r)-3-methoxy-3-methyl-1-(4- methyl-4H-1...)
Affinity DataKd:  13nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710679((2-(3-((1s,3s)-3-hydroxy-3-methyl-1-(4- methyl-4H-...)
Affinity DataKd:  170nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710680(2-(3-((1s,3s)-3-fluoro-3-methyl-1-(4- methyl-4H-1,...)
Affinity DataKd:  9.80nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710681(2-(3-((1r,3r)-3-fluoro-3-methyl-1-(4-methyl- 4H-1,...)
Affinity DataKd:  16nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710684(2-(3-((1s,3s)-3-methyl-1-(4-methyl-4H- 1,2,4-triaz...)
Affinity DataKd:  2.30nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710685(2-(3-((1r,3r)-3-methyl-1-(4-methyl-4H- 1,2,4-triaz...)
Affinity DataKd:  1.70nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710686(2-(3-((1r,3r)-3-fluoro-1-(4-methyl-4H-1,2,4- triaz...)
Affinity DataKd:  8nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710687((S)-6-(1-(cyclobutylamino)ethyl)-2-(3-(3,3- difluo...)
Affinity DataKd:  3.80nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710688((R)-6-(1-(cyclobutylamino)ethyl)-2-(3-(3,3- difluo...)
Affinity DataKd:  24nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710689(2-(3-(3,3-dimethyl-1-(4-methyl-4H-1,2,4- triazol-3...)
Affinity DataKd:  7.5nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710690(2-(3-(2-(4-methyl-4H-1,2,4-triazol-3- yl)spiro[3.3...)
Affinity DataKd:  20nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710691((S)-6-((2-isopropyl-4-methylpiperazin-1- yl)methyl...)
Affinity DataKd:  78nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710698(2-(6-((3,3-difluorocyclobutyl)amino)-4- ((1r,3r)-3...)
Affinity DataKd:  11nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710699(2-(6-((3,3-difluorocyclobutyl)amino)-4- ((1s,3s)-3...)
Affinity DataKd:  16nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710700(2-(6-(cyclohexylamino)-4-((1r,3r)-3-methyl- 1-(4-m...)
Affinity DataKd:  20nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710702(2-(6-(cyclopentylamino)-4-((1r,3r)-3- methyl-1-(4-...)
Affinity DataKd:  11nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710703(2-(6-(cyclopentylamino)-4-((1s,3s)-3- methyl-1-(4-...)
Affinity DataKd:  6.5nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710704(2-(6-(cyclopentyloxy)-4-((1s,3s)-3-methyl- 1-(4-me...)
Affinity DataKd:  15nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710708(2-(3-(3-(4-methyl-4H-1,2,4-triazol-3- yl)oxetan-3-...)
Affinity DataKd:  440nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710711(2-(3-(3,3-difluoro-1-(4-methyl-4H-1,2,4- triazol-3...)
Affinity DataKd:  20nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710712(2-(4-(3,3-difluoro-1-(4-methyl-4H-1,2,4- triazol-3...)
Affinity DataKd:  1.10nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710713((1S,3r)-3-(3-(6-(((S)-2-isopropyl-4- methylpiperaz...)
Affinity DataKd:  19nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710714((1R,3s)-3-(3-(6-(((S)-2-isopropyl-4- methylpiperaz...)
Affinity DataKd:  81nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710715(2-(3-(6-(4-methyl-4H-1,2,4-triazol-3-yl)-2- oxaspi...)
Affinity DataKd:  68nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710716((S)-2-(3-(6-(4-methyl-4H-1,2,4-triazol-3- yl)-2-ox...)
Affinity DataKd:  81nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710717(2-(6-(cyclobutylamino)-4-((1S,3S)-3- methyl-1-(4-m...)
Affinity DataKd:  0.530nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710718(2-(6-(cyclobutylamino)-4-((1R,3R)-3- methyl-1-(4-m...)
Affinity DataKd:  1nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710719(2-(6-(cyclopentylamino)-4-((1S,3S)-3- methoxy-1-(4...)
Affinity DataKd:  23nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710720(2-(6-(cyclopentylamino)-4-((1R,3R)-3- methoxy-1-(4...)
Affinity DataKd:  220nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-C(Human)
Genentech

US Patent
LigandPNGBDBM710721(2-(6-(cyclobutylamino)-4-((S)-3-methyl-1- (4-methy...)
Affinity DataKd:  34nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent

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