Compile Data Set for Download or QSAR
Report error Found 13 for UniProtKB: Q9UBN4
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519465(CHEMBL4466522)
Affinity DataIC50: 0.0120nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at -100 mV by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519465(CHEMBL4466522)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at +100 mV by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 1/4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519465(CHEMBL4466522)
Affinity DataIC50: 0.0330nMAssay Description:Inhibition of human TRPC4/human TRPC1 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519465(CHEMBL4466522)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fluo-4AM dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50647393(CHEMBL4752870)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50647396(CHEMBL5597024)
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519473(CHEMBL4546097)
Affinity DataIC50: 46nMAssay Description:Inhibition of human TRPC4 expressed in human T-REx-293 cells coexpressing M1 receptor assessed as reduction in calcium influx by Fluo-4AM dye based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 1/4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519489(CHEMBL4450705)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at TRPC4/TRPC1 in human A498 cells assessed as reduction in englerin A-induced calcium entry preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599832(CHEMBL5201831)
Affinity DataIC50: 65nMAssay Description:Inhibition of TRPC4 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50: 290nMAssay Description:Inhibition of Englerin-activated human TRPC4 channel expressed in HEK293 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50595298(CHEMBL5207902)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of human TRPC4 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50450500(CHEMBL4164465)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRPC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM49021(N-(furan-2-ylmethyl)-1-(phenylmethyl)benzimidazol-...)
Affinity DataIC50: 7.72E+4nMAssay Description:Inhibition of human TRPC4 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed