Compile Data Set for Download or QSAR
Report error Found 360 of affinity data for UniProtKB/TrEMBL: Q9NZ08
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  8.49E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  6.22E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245391(CHEMBL4095882)
Affinity DataIC50: 33nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant ERAP1 using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence microplate reader met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant ERAP1 using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence microplate reader met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human ERAP1 using L-AMC as substrate incubated for 5 to 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571866(CHEMBL4862557)
Affinity DataIC50: 34nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 43nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 43nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50635821(CHEMBL5517929)
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 48nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245400(CHEMBL4099107)
Affinity DataIC50: 48nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 52nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245390(CHEMBL4077855)
Affinity DataIC50: 65nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245401(CHEMBL4103640)
Affinity DataIC50: 71nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245383(CHEMBL4104383)
Affinity DataIC50: 98nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571865(CHEMBL4863142)
Affinity DataIC50: 99nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245388(CHEMBL4081073)
Affinity DataIC50: 102nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571867(CHEMBL4875461)
Affinity DataIC50: 115nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571872(CHEMBL4864508)
Affinity DataIC50: 120nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245399(CHEMBL4069425)
Affinity DataIC50: 126nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50570849(CHEMBL4854733)
Affinity DataIC50: 140nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50570849(CHEMBL4854733)
Affinity DataIC50: 141nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245389(CHEMBL4085707)
Affinity DataIC50: 143nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571874(CHEMBL4855038)
Affinity DataIC50: 151nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245348(CHEMBL4099693)
Affinity DataIC50: 155nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245382(CHEMBL4080145)
Affinity DataIC50: 178nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 186nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 190nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571868(CHEMBL4854530)
Affinity DataIC50: 262nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571862(CHEMBL4847534)
Affinity DataIC50: 275nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50570851(CHEMBL4853049)
Affinity DataIC50: 324nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50570851(CHEMBL4853049)
Affinity DataIC50: 330nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50245354(CHEMBL4097268)
Affinity DataIC50: 340nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50571856(CHEMBL4850551)
Affinity DataIC50: 377nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50570850(CHEMBL4877339)
Affinity DataIC50: 410nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50570850(CHEMBL4877339)
Affinity DataIC50: 417nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50601035(CHEMBL5194003)
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus infected Hi-5 insect cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661074(US20240101542, Compound 21 | (S)-N-hydroxy-2-(4-((...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661075(US20240101542, Compound 22 | (S)-N-hydroxy-2-(4-((...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661076(US20240101542, Compound 23 | (S)-N-hydroxy-3-(4-ph...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661077(US20240101542, Compound 24 | (S)-N-hydroxy-3-(4-me...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661078(US20240101542, Compound 25 | (S)-N-hydroxy-3-(4-me...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661079(US20240101542, Compound 26 | (2S)-3-(4-tert-butoxy...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661080(US20240101542, Compound 27 | (2S)-3-(4-tert-butoxy...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

TargetEndoplasmic reticulum aminopeptidase 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM661081(US20240101542, Compound 28 | (S)-4-(5-(N-((1-(1-(h...)
Affinity DataIC50: 500nMAssay Description:The enzymatic activity of ERAP1 or 2 was assayed using L-AMC (L-Leucine-7-amido-4-methylcoumarin hydrochloride) or R-AMC (L-Arginine-7-amido-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
Go to US Patent

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