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TargetSodium channel protein type 3 subunit alpha(Human)
University of California

US Patent
LigandPNGBDBM168436(US9675591, SKA-19)
Affinity DataEC50:  2.20E+3nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
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TargetSodium channel protein type 3 subunit alpha(Human)
University of California

US Patent
LigandPNGBDBM50505257(CHEMBL4471012)
Affinity DataKd:  110nMAssay Description:Binding affinity to human recombinant Nav1.3 by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
University of California

US Patent
LigandPNGBDBM76858(US9694002, 580 | US9546164, 580)
Affinity DataKd:  180nMAssay Description:Binding affinity to human recombinant Nav1.3 by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
University of California

US Patent
LigandPNGBDBM50521571(CHEMBL4464990)
Affinity DataKd: >1.00E+3nMAssay Description:Inhibition of full length human Nav1.3 expressed in HEK293 cells at -60 mV holding potential by manual patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM71381(US9694002, 440 | US9546164, 440)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71340(US9694002, 411 | US9546164, 411)
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71351(US9694002, 422 | US9546164, 422)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71341(US9694002, 412 | US9546164, 412)
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70878(US9694002, 52 | US9546164, 52)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71055(US9694002, 202 | US9546164, 202)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71063(US9694002, 208 | US9546164, 208)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71101(US9694002, 236 | US9546164, 236)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71193(US9694002, 300 | US9546164, 300)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70836(US9694002, 23)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70848(US9694002, 29)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71062(US9694002, 207 | US9546164, 207)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71064(US9694002, 209 | US9546164, 209)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71067(US9694002, 211 | US9546164, 211)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71061(US9694002, 206 | US9546164, 206)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70855(US9694002, 34)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70876(US9694002, 51 | US9694002, 50 | US9546164, 50)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70982(US9694002, 136 | US9546164, 136)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71065(US9694002, 210 | US9546164, 210)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71192(US9694002, 299 | US9546164, 299)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71222(US9694002, 322 | US9546164, 322)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71224(US9694002, 323 | US9546164, 323)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71006(US9694002, 155 | US9546164, 155)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71271(US9694002, 352 | US9546164, 352)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71285(US9694002, 361 | US9546164, 361)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70866(US9694002, 42)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70876(US9694002, 51 | US9694002, 50 | US9546164, 50)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70946(US9694002, 107 | US9546164, 107)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70985(US9694002, 137 | US9546164, 137)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71328(US9694002, 400 | US9546164, 400)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71352(US9694002, 423 | US9546164, 423)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71546(US9694002, 556 | US9546164, 556)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71107(US9694002, 238 | US9546164, 238)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71136(US9694002, 259 | US9546164, 259)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71211(US9694002, 312 | US9546164, 312)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71465(US9694002, 496)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71512(US9694002, 531 | US9546164, 531)
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71017(US9694002, 165 | US9546164, 165)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71186(US9694002, 295 | US9546164, 295)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71209(US9694002, 310 | US9546164, 310)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71510(US9694002, 530 | US9694002, 529 | US9546164, 530)
Affinity DataIC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70856(US9694002, 35)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM70967(US9694002, 122 | US9546164, 122)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71111(US9694002, 240 | US9546164, 240)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71228(US9694002, 325 | US9546164, 325)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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LigandPNGBDBM71349(US9694002, 420 | US9546164, 420)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
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