Compile Data Set for Download or QSAR
Report error Found 776 of affinity data for UniProtKB/TrEMBL: Q9NUW8
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM60991(BDBM50425048 | US9402842, 14)
Affinity DataKd:  3.10E+4nMAssay Description:Binding affinity to recombinant Tdp1 (unknown origin) using 3'-phosphate(GATCTAAAAGACTT) as substrate by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507140(CHEMBL4440514)
Affinity DataKd:  1.07E+4nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507153(CHEMBL4551119)
Affinity DataKd:  7.14E+3nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507150(CHEMBL4440114)
Affinity DataKd:  9.46E+3nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507154(CHEMBL4533174)
Affinity DataKd:  3.11E+4nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507139(CHEMBL4446104)
Affinity DataKd:  8.65E+3nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507152(CHEMBL4436400)
Affinity DataKd:  4.46E+4nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507156(CHEMBL4475772)
Affinity DataKd:  3.52E+4nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507151(CHEMBL4438274)
Affinity DataKd:  7.02E+3nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507155(CHEMBL4587610)
Affinity DataKd:  6.20E+3nMAssay Description:Binding affinity to recombinant human Tdp1 (149 to 608 residues) expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50534270(CHEMBL4464463)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546508(CHEMBL4746230)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 20 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546509(CHEMBL4760174)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50589478(CHEMBL5187480)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human TDP1 measured by real-time oligonucleotide biosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli Rosetta2(DE3) using 3'-FITC labeled 13-mer DNA as substrate by Gyrasol ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50534268(CHEMBL4571632)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50463376(CHEMBL4244758)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507151(CHEMBL4438274)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507151(CHEMBL4438274)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human TDP1 measured by real-time oligonucleotide biosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546512(CHEMBL4799682)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546515(CHEMBL4756604)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507140(CHEMBL4440514)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546513(CHEMBL4761724)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546514(CHEMBL4750455)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50463381(CHEMBL4241424)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50463368(CHEMBL4250901)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507150(CHEMBL4440114)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50463384(CHEMBL4242066)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507155(CHEMBL4587610)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546511(CHEMBL4745693)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530468(CHEMBL4436247)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530468(CHEMBL4436247)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50540219(CHEMBL4642359)
Affinity DataIC50: 99nMAssay Description:Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530462(CHEMBL4435210)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530462(CHEMBL4435210)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM11995(2-chloro-5-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic ac...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Tdp1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530469(CHEMBL4442276)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530469(CHEMBL4442276)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50546510(CHEMBL4797909)
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50463372(CHEMBL3356739)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507156(CHEMBL4475772)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507139(CHEMBL4446104)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50232848(CHEMBL4084310)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50463379(CHEMBL4243917)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507153(CHEMBL4551119)
Affinity DataIC50: 172nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50232847(CHEMBL4090202)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530467(CHEMBL4467521)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50530467(CHEMBL4467521)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50507152(CHEMBL4436400)
Affinity DataIC50: 192nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
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