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TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755056(US20250213546, Compound AD-2441)
Affinity DataKd:  1.05E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755057(US20250213546, Compound AD-0029)
Affinity DataKd:  3.56E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755058(US20250213546, Compound AD-6772)
Affinity DataKd:  8.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755059(US20250213546, Compound AD-8007)
Affinity DataKd:  8.90E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755060(US20250213546, Compound AD-1363)
Affinity DataKd:  8.50E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755061(US20250213546, Compound AD-8972)
Affinity DataKd:  1.16E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755062(US20250213546, Compound AD-7346)
Affinity DataKd:  5.30E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755063(US20250213546, Compound AD-3766)
Affinity DataKd:  6.70E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755064(US20250213546, Compound AD-4859)
Affinity DataKd:  5.20E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM755065(US20250213546, Compound AD-5584)
Affinity DataKd:  1.61E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50517061(CHEMBL4467131)
Affinity DataIC50: 0.00280nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578397(CHEMBL4855352 | US20240009175, Compound 33)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578398(CHEMBL4859117 | US20240009175, Compound 35)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50517065(CHEMBL4550594)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50517069(CHEMBL4449652)
Affinity DataIC50: 0.463nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50517059(CHEMBL4535842)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human MDA-MB-468 cells assessed as 13C-acetate incorporation incubated for 5 hrs measured under hypoxic conditions by LCMS ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578397(CHEMBL4855352 | US20240009175, Compound 33)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578398(CHEMBL4859117 | US20240009175, Compound 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578399(CHEMBL4870878 | US20240009175, Compound 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578399(CHEMBL4870878 | US20240009175, Compound 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578397(CHEMBL4855352 | US20240009175, Compound 33)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578398(CHEMBL4859117 | US20240009175, Compound 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578399(CHEMBL4870878 | US20240009175, Compound 37)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Drexel University

US Patent
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
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