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Report error Found 27 for UniProtKB: Q9JHJ5
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKd:  0.813nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor in rat cortex preparations using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataKd:  0.794nMAssay Description:Compound was evaluated for binding to Serotonin 5-hydroxytryptamine 3 receptor in N1E cells using [3H]- -Tropisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKd:  1.30nMAssay Description:Compound was evaluated for binding to 5-hydroxytryptamine 3 receptor in N1E cells using [3H]- -Tropisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50449568(CHEMBL2448558)
Affinity DataKd:  3.20nMAssay Description:Compound was evaluated for binding to Serotonin 5-hydroxytryptamine 3 receptor in N1E cells using [3H]- -Tropisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKd:  20nMAssay Description:Compound was evaluated for binding to 5-hydroxytryptamine 3 receptor in N1E cells using [3H]- -Tropisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50391335(CHEMBL143197)
Affinity DataKd:  0.631nMAssay Description:Compound was evaluated for binding to Serotonin 5-hydroxytryptamine 3 receptor in N1E cells using [3H]- -Tropisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKd:  1.40nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKd:  224nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50227348(CHEMBL41096 | SDZ-206-830)
Affinity DataKd:  0.158nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptor in the rabbit heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50227350(NORTROPISETRON | SDZ-206-792)
Affinity DataKd:  0.724nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKd:  13nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014407(2-Piperazin-1-yl-quinoline (Quipazine) | CHEMBL187...)
Affinity DataKd:  2nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM82561(TROPANYL 3,5-DICHLOROBENZOATE | CAS_40796-97-2 | T...)
Affinity DataKd:  6.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50449568(CHEMBL2448558)
Affinity DataKd:  3.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50013046(CHEMBL93064 | 1-(Thiophen-2-ylmethyl)guanidine | N...)
Affinity DataKi: >1nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50013045(CHEMBL290266 | 3-[2-(2-Methyl-imidazol-1-ylmethyl)...)
Affinity DataKi: >1nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50013044(CHEMBL288640 | N-Benzyl-guanidine | 1-Benzylguanid...)
Affinity DataKi: >1nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50013040(CHEMBL93244 | N-[4-(1H-Indol-3-yl)-thiazol-2-ylmet...)
Affinity DataKi: >1nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  1.30nMAssay Description:The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50013043(CHEMBL290938 | 3-[2-(5-Methyl-1H-imidazol-4-ylmeth...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50013038(CHEMBL93964 | 1-(Pyridin-3-ylmethyl)guanidine | N-...)
Affinity DataKi:  82nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50013042(CHEMBL92180 | N-(4-Methyl-thiazol-2-ylmethyl)-guan...)
Affinity DataKi:  116nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Affinity DataKi:  3.16E+3nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor in NG cells 108-15More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056944(4-Fluoro-N-{2-[4-(1,2,3,4-tetrahydro-naphthalen-1-...)
Affinity DataKi:  3.47E+3nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor in NG cells 108-15More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3B(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056947(N-{2-[4-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-piper...)
Affinity DataKi:  3.47E+3nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor in NG cells 108-15More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50187377(N-(3-(4-(4-(cyclohexylmethylsulfonamido)butyl)pipe...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to mouse 5HT3 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed