Compile Data Set for Download or QSAR
Report error Found 33 of affinity data for UniProtKB/TrEMBL: Q99KQ4
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of NAMPT in mouse cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011266(CHEMBL3260358)
Affinity DataEC50:  70nMAssay Description:Inhibition of NAMPT in mouse cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515548(CHEMBL4458472)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515544(CHEMBL4535593)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236221(CHEMBL4078882)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515540(CHEMBL4470375)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515543(CHEMBL4464821)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataIC50: 24nMAssay Description:Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515551(CHEMBL4446772)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236223(CHEMBL4083606)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515552(CHEMBL4469394)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515556(CHEMBL4555764)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236222(CHEMBL4101611)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236224(CHEMBL4088492)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515541(CHEMBL4590810)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515545(CHEMBL4440197)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515546(CHEMBL4577703)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515547(CHEMBL4444551)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236216(CHEMBL4064240)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515542(CHEMBL4569066)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236218(CHEMBL4094769)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011266(CHEMBL3260358)
Affinity DataIC50: 59nMAssay Description:Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515553(CHEMBL4567518)
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515550(CHEMBL4462010)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50236215(CHEMBL4087071)
Affinity DataIC50: 269nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2019
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515549(CHEMBL4555772)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515554(CHEMBL4561248)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50515555(CHEMBL4070645)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed