Compile Data Set for Download or QSAR
Report error Found 309 for UniProtKB: Q99594
LigandPNGBDBM626316(2-[[[7-(4-isopropylphenyl)-2,3- dihydrobenzofuran...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626317(2-[[[7-(4-isopropylphenyl)-2,3- dihydrobenzofuran...)
Affinity DataEC50:  1.80E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626318(2-[[[4-cyano-7-(4-isopropylphenyl)- 2,3-dihydrobe...)
Affinity DataEC50:  6.22E+3nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626319(2-[[[4-cyano-7-(4-isopropylphenyl)- 2,3-dihydrobe...)
Affinity DataEC50:  1.30E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626320(2-[[[4-cyano-7-(4-isopropylphenyl)- 2,3-dihydrobe...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626321(2-[[[4-cyano-7-(4-isopropylphenyl)- 2,3-dihydrobe...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626322(2-[[[4-cyano-7-(4-isopropylphenyl)- 2,3-dihydrobe...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626323(methyl 2-[[[4-cyano-7-(4- isopropylphenyl)-2,3- ...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626324(US11787775, Compound 29 | 2-[[[4-cyano-7-(4-isopro...)
Affinity DataEC50:  2.20E+3nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626325(1-[[[4-cyano-7-(4-isopropylphenyl)- 2,3-dihydrobe...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626326(7-(4-isopropylphenyl)-5-[(2- methylene-3-oxo-buty...)
Affinity DataEC50:  200nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626327(2-[[[4-(hydroxymethyl)-7-(4- isopropylphenyl)-2,3...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626328(2-[[[4-(hydroxymethyl)-7-(4- isopropylphenyl)-2,3...)
Affinity DataEC50:  2.20E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626329(2-[[[4-(hydroxymethyl)-7-(4- isopropylphenyl)-2,3...)
Affinity DataEC50:  3.40E+3nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626330(2-[[[4-cyano-7-[4- (trifluoromethyl)phenyl]-2,3- ...)
Affinity DataEC50:  1.10E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626331(US11787775, Compound 16-C)
Affinity DataEC50:  5.90E+3nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626332(US11787775, Compound 16-D)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626333(2-[[[4-cyano-7-[4- (trifluoromethoxy)phenyl]-2,3-...)
Affinity DataEC50:  7.80E+3nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626334(2-[[[4-cyano-7-[4-(1,1- difluoroethyl)phenyl]-2,3...)
Affinity DataEC50:  1.50E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626335(2-[[[4-(4-isopropylphenyl)-6,7- dihydrofuro[3,2-d...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626336(2-[[[4-fluoro-7-(4-isopropylphenyl)- 2,3-dihydrob...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626337(2-[[[4-cyano-7-(4-isopropylphenyl)- 2,3-dihydrofu...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626338(2-[[[7-cyano-4-[4-(1,1- difluoroethyl)phenyl]-1,3...)
Affinity DataEC50:  1.50E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626339(2-[[[6-methoxy-5-[(E)-2-[trans-4- (trifluoromethy...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626341(2-[[[4-cyano-7-(2,6-difluoro-4- isopropyl-phenyl)...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626342(2-[[[4-cyano-7-(2-fluoro-4- isopropyl-phenyl)-2,3...)
Affinity DataEC50:  8.20E+3nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626343(2-[[[4-carbamoyl-7-(4- isopropylphenyl)-2,3- dih...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626344(2-[[[7-cyano-4-[4- (trifluoromethoxy)phenyl]-1,3-...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626345(2-[[[4-cyano-7-(5-isopropyl-2- pyridyl)-2,3-dihyd...)
Affinity DataEC50: >5.00E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

LigandPNGBDBM626346(2-[[[7-(4-isopropylphenyl)-4- methylsulfonyl-2,3-...)
Affinity DataEC50:  1.70E+4nMAssay Description:Table 4-5: Purified His-tagged TEAD protein (YAP Binding Domain, amino acids 217-447) is pre-incubated with Europium labelled anti-His antibody trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50600846(CHEMBL5170406)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to human TEAD3 (216 to 435 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50626272(CHEMBL5408794)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to TEAD 3 (unknown origin) assessed as dissociation constant by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50626273(CHEMBL5406847)
Affinity DataKd:  9.80E+3nMAssay Description:Binding affinity to TEAD 3 (unknown origin) assessed as dissociation constant by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50629174(CHEMBL5422959)
Affinity DataIC50: 3nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM699325(2-chloro-N-methyl-N-((1-(4- (trifluoromethoxy)phen...)
Affinity DataIC50: 3.5nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630290(CHEMBL5438256)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630292(US12110276, Compound 49 | CHEMBL5408536)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50629172(CHEMBL5401444)
Affinity DataIC50: 4nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630292(US12110276, Compound 49 | CHEMBL5408536)
Affinity DataIC50: 4.25nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630291(US12110276, Compound 48 | CHEMBL5411200)
Affinity DataIC50: 4.80nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630291(US12110276, Compound 48 | CHEMBL5411200)
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50629173(CHEMBL5415215)
Affinity DataIC50: 7nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50629170(CHEMBL5419829)
Affinity DataIC50: 8nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM699395(cyclobuten-1-yl-[3-[4- (hydroxymethyl)-1-[4- (trif...)
Affinity DataIC50: 8.70nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM699408((E)-3-chloro-1-[3-[4-(hydroxymethyl)- 1-[4- (trifl...)
Affinity DataIC50: 8.80nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630294(US12110276, Compound 112 | CHEMBL5432828)
Affinity DataIC50: 8.90nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630294(US12110276, Compound 112 | CHEMBL5432828)
Affinity DataIC50: 9nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50629175(CHEMBL5400400)
Affinity DataIC50: 9nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50630293(US12110276, Compound 86 | CHEMBL5403826)
Affinity DataIC50: 9.70nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM699469(Cyclobut-1-en-1-yl(3-(1-(4- (trifluoromethoxy)phen...)
Affinity DataIC50: 10nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

Displayed 1 to 50 (of 309 total ) | Next | Last >>
Jump to: