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TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataIC50: 36nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataIC50: 54nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataIC50: 65nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 340nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 340nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataIC50: 620nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM13064(4-(4-fluorophenyl)-1-(4-methanesulfonylphenyl)-3-(...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50087247(5-{4-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-amino...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of bovine Carbonic anhydrase IV determined by esterase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50084563(5-[4-Amino-benzenesulfonylimino]-4-methyl-4,5-dihy...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50084563(5-[4-Amino-benzenesulfonylimino]-4-methyl-4,5-dihy...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of bovine carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114157((R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50080684(5-(4-aminophenylsulfonylimino)-4-methyl-4,5-dihydr...)
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114120((R)-4-((2R,6S,7S,8S,10R,12S)-10,13-Dimethyl-3,7,12...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114129(4-((6R,7S,8S,10R,11S,12S,14S,15R)-3,12-Di(R)-hydro...)
Affinity DataKi:  1.20nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50088778(N,N-dialkylthio-carbonylsulfenylamino derivative |...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of bovine carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114147((R)-4-((5S,6R,8S,9S,12S,14R,17S)-7-Hydroxy-3-(R)-h...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11631(5-(4-Amino-3,5-dibromobenzenesulfonamido)-1,3,4-th...)
Affinity DataKi:  1.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11626(2-N-(4-amino-3-bromo-5-fluorobenzene)-1,3,4-thiadi...)
Affinity DataKi:  1.90nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11628(5-(4-Amino-3,5-dichlorobenzenesulfonamido)-1,3,4-t...)
Affinity DataKi:  1.90nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  2nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11629(5-{[(4-amino-3-bromo-5-chlorophenyl)sulfonyl]amino...)
Affinity DataKi:  2nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14722(Sulfonamide, 8 | 1-N-[5-Sulfamoyl-1,3,4-thiadiazol...)
Affinity DataKi:  2nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14722(Sulfonamide, 8 | 1-N-[5-Sulfamoyl-1,3,4-thiadiazol...)
Affinity DataKi:  2nM ΔG°:  -48.8kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2/3/4/6(Bovine)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50070606(CHEMBL3408993)
Affinity DataKi:  2nMAssay Description:Inhibition of bovine carbonic anhydrase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114130((1R,2R)-4-((8S,9S,12R,14R,17S)-3-(R)-Hydroxy-10,13...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114193((R)-4-((7S,8S,9S,10R,12R,14S,17R)-3,7-Dihydroxy-10...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11627(2-N-(4-amino-3-fluoro-5-iodobenzene)-1,3,4-thiadia...)
Affinity DataKi:  2.10nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14718(2,4,6-trimethyl-1-{4-[(5-sulfamoyl-1,3,4-thiadiazo...)
Affinity DataKi:  2.10nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114180((1R,2R,5R)-4-((1R,5S,8S,10R,11S,12S)-3,12-Dihydrox...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM50114213((1R,5R)-4-((5S,8S,9R,11R,17S)-3-Hydroxy-10-methyl-...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11632(5-{[(4-amino-3-bromo-5-iodophenyl)sulfonyl]amino}-...)
Affinity DataKi:  2.30nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11633(5-(4-Amino-3,5-diiodobenzenesulfonamido)-1,3,4-thi...)
Affinity DataKi:  2.30nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14723(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Affinity DataKi:  2.30nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11622(2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  2.40nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11623(5-(4-Amino-3-bromobenzenesulfonamido)-1,3,4-thiadi...)
Affinity DataKi:  2.40nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14736(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Affinity DataKi:  2.40nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11621(2-N-(4-amino-3-fluorobenzene)-1,3,4-thiadiazole-2,...)
Affinity DataKi:  2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11624(2-N-(4-amino-3-iodobenzene)-1,3,4-thiadiazole-2,5-...)
Affinity DataKi:  2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11630(2-N-(4-amino-3-chloro-5-iodobenzene)-1,3,4-thiadia...)
Affinity DataKi:  2.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14719(2,4-dimethyl-6-(propan-2-yl)-1-{4-[(5-sulfamoyl-1,...)
Affinity DataKi:  3nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14727(2-methyl-4,6-diphenyl-1-{4-[(5-sulfamoyl-1,3,4-thi...)
Affinity DataKi:  3nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11427(CHEMBL108380 | 5-{[(4-methylphenyl)sulfonyl]amino}...)
Affinity DataKi:  3nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM14728(2-ethyl-4,6-diphenyl-1-{4-[(5-sulfamoyl-1,3,4-thia...)
Affinity DataKi:  3.80nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Bruker-Axs

Curated by ChEMBL
LigandPNGBDBM11616(aminobenzolamide deriv. 40 | 5-(4-Acetamido-3-fluo...)
Affinity DataKi:  4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2006
Entry Details Article
PubMed
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