Compile Data Set for Download or QSAR
Report error Found 2 of affinity data for UniProtKB/TrEMBL: Q92888
TargetRho guanine nucleotide exchange factor 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  1.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRho guanine nucleotide exchange factor 1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50056922(cid_73677 | CHEMBL173530 | 1,4-Dihydroxy-10-methox...)
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of p115 DHPH22 domain (395 to 766 residues) (unknown origin) interaction with GDP-loaded His-tagged RhoA F25N mutant (1 to 180 residues) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed