Compile Data Set for Download or QSAR
Report error Found 12 of affinity data for UniProtKB/TrEMBL: Q92824
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50533413(CHEMBL3126388)
Affinity DataKi:  0.120nMAssay Description:Inhibition of recombinant C-terminal truncated human SPC6 expressed in drosophila Schneider 2 cells after 1 hr by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50303774(phenylacetyl-Arg-Val-Arg-4-amidinobenzylamide | CH...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50303775((S)-2-acetamido-N-((S)-1-((S)-1-(4-carbamimidoylbe...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50303776(N-((6S,9S,12S)-1,17-diamino-6-(4-carbamimidoylbenz...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50303777((S)-5-guanidino-N-((S)-1-((S)-5-guanidino-1-(3-gua...)
Affinity DataKi:  85nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50303778((S)-N-((1-carbamimidoylpiperidin-4-yl)methyl)-5-gu...)
Affinity DataKi:  173nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50270060(TPQRARRRKKRT | CHEMBL455792)
Affinity DataKi:  188nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50270054(TPRARRRKKRT | CHEMBL502642)
Affinity DataKi:  232nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50270067(TPQRARRRKKRW | CHEMBL503520)
Affinity DataKi:  433nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50269901(TPRARRRKKRI | CHEMBL525748)
Affinity DataKi:  492nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50270069(TPQRARRRKKRY | CHEMBL499438)
Affinity DataKi:  649nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 5(Human)
Centre Hospitalier Universitaire Vaudois (Chuv)

Curated by ChEMBL
LigandPNGBDBM50270068(TPQRARRRKKRF | CHEMBL500184)
Affinity DataKi:  806nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed