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TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109275(US8609622, 2)
Affinity DataIC50: 1.42nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109278(US8609622, 5)
Affinity DataIC50: 1.49nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50: 3.31nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109275(US8609622, 2)
Affinity DataIC50: 3.65nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109279(US8609622, 7)
Affinity DataIC50: 4.58nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50: 6.35nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50: 6.92nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302617((2S,3R,4R,5S)-2-[4-Chloro-3-(4-hydroxy-benzyl)-phe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109276(US8609622, 3)
Affinity DataIC50: 8.08nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109280(US8609622, 9)
Affinity DataIC50: 9.28nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302616((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(2-hydroxyethoxy)be...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109274(US8609622, 1)
Affinity DataIC50: 9.53nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302625((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302625((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302615((2S,3R,4R,5S)-2-{4-Chloro-3-[4-(2-methoxy-ethoxy)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302624((2S,3R,4R,5S)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 19nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302609((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302623((2S,3R,4R,5S)-2-(3-(4-Ethoxybenzyl)-4-methylphenyl...)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302619([2-Chloro-5-((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-m...)
Affinity DataIC50: 57nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302613((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(thiazol-2-yloxy)be...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302614((2R,3S,4S,5R)-2-(4-Chloro-3-(4-((S)-1-methylpyrrol...)
Affinity DataIC50: 92nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302604((3S,4R,5R,6S)-6-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302621((2S,3R,4R,5S)-2-(4-Chloro-3-(4-methoxyphenylthio)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302605((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302606((2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302622((2S,3R,4R,5S)-2-(3-(4-Ethoxybenzyl)phenyl)-6-metho...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302608((3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethox...)
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302612(O-4-(2-Chloro-5-((2S,3R,4R,5S)-3,4,5-trihydroxy-6-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50340014(4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mouse SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302620((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxyphenoxy)pheny...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302618((2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxy...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302607((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302610((2R,3S,4S,5R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50302611((2S,3R,4S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed