Compile Data Set for Download or QSAR
Report error Found 85 of affinity data for UniProtKB/TrEMBL: Q91ZY1
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataKd:  134nMAssay Description:Binding affinity to rat H4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509065(CHEMBL4439142)
Affinity DataEC50:  26nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataEC50:  3.72E+3nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509064(CHEMBL4445423)
Affinity DataEC50:  145nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509067(CHEMBL4518374)
Affinity DataEC50:  646nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509074(CHEMBL4543119)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509075(CHEMBL4437371)
Affinity DataEC50:  23nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509067(CHEMBL4518374)
Affinity DataEC50:  93nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataEC50:  741nMAssay Description:Agonist activity at rat H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50419443(CHEMBL1196470)
Affinity DataEC50:  3.39E+4nMAssay Description:Agonist activity at rat H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509074(CHEMBL4543119)
Affinity DataEC50:  331nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataEC50:  158nMAssay Description:Agonist activity at rat H4R expressed in in HEK293T cells by CRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  22nMAssay Description:Binding affinity to rat H4R expressed in HEK293T-SF-His6-CRE-Luc cells by saturation binding studyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509064(CHEMBL4445423)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22880(2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | Methy...)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at rat histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50483137(CHEMBL1632413)
Affinity DataEC50:  10nMAssay Description:Agonist activity at rat histamine H4 receptor by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataEC50:  158nMAssay Description:Agonist activity at rat histamine H4 receptor by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50483138(CHEMBL1632414)
Affinity DataEC50:  200nMAssay Description:Agonist activity at rat histamine H4 receptor by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50483139(CHEMBL1632412)
Affinity DataEC50:  501nMAssay Description:Agonist activity at rat histamine H4 receptor by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  34nMAssay Description:Binding affinity to rat H4R expressed in HEK293T-SF-His6-CRE-Luc cells by kinetic binding studyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509071(CHEMBL4455324)
Affinity DataEC50:  34nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509075(CHEMBL4437371)
Affinity DataEC50:  191nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509071(CHEMBL4455324)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50413498(UR-PI294 | CHEMBL475621)
Affinity DataEC50:  3.31E+3nMAssay Description:Agonist activity at rat H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataEC50:  295nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509065(CHEMBL4439142)
Affinity DataEC50:  0.646nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataEC50:  5.01E+4nMAssay Description:Agonist activity at rat H4R expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2 by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  34nMAssay Description:Binding affinity to rat H4R expressed in HEK293T-SF-His6-CRE-Luc cells assessed as kinetically derived dissociation constant by saturation binding st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509078(CHEMBL4443126)
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  22nMAssay Description:Binding affinity to rat H4R expressed in HEK293T-SF-His6-CRE-Luc cells assessed as equilibrium dissociation constant by saturation binding studyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509072(CHEMBL4454158)
Affinity DataEC50:  17nMAssay Description:Agonist activity at rat H4R expressed in HEK293T-beta-arr2-rH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509078(CHEMBL4443126)
Affinity DataEC50:  0.617nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509072(CHEMBL4454158)
Affinity DataEC50:  0.0501nMAssay Description:Agonist activity at rat H4R expressed in HEK293-SF-rH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataEC50:  5.25E+4nMAssay Description:Agonist activity at rat H4R by [35S]-GTPgammaS-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415770(CHEMBL1079516)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM26399(14-fluoro-6-(piperazin-1-yl)-3,5-diazatricyclo[9.4...)
Affinity DataKi:  1.45nM ΔG°:  -50.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50361015(CHEMBL592379)
Affinity DataKi:  1.55nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity of compound towards rat histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415769(CHEMBL1089390)
Affinity DataKi:  2.63nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415767(CHEMBL1077276)
Affinity DataKi:  2.69nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415768(CHEMBL1089040)
Affinity DataKi:  3.24nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50133004((7-amino-1H-indol-2-yl)(4-methylpiperazin-1-yl)met...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity of compound towards rat histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM26226((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)
Affinity DataKi:  3.40nM ΔG°:  -48.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM26398(6-[3-(methylamino)azetidin-1-yl]-3,5-diazatricyclo...)
Affinity DataKi:  3.60nM ΔG°:  -48.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM26396(A-943931 | 6-[(3R)-3-aminopyrrolidin-1-yl]-3,5-dia...)
Affinity DataKi:  3.80nM ΔG°:  -48.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM26391(5-chloro-2-(piperazin-1-ylcarbonyl)-1H-indole | JN...)
Affinity DataKi:  4nM ΔG°:  -47.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  4.27nMAssay Description:Displacement of [3H]-histamine from rat H4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 85 total ) | Next | Last >>
Jump to: