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Report error Found 32 of affinity data for UniProtKB/TrEMBL: Q91WN4
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072078(CHEMBL3407905)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549707(CHEMBL4781856)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549706(CHEMBL4744083)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549704(CHEMBL4764931)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549714(CHEMBL4762572)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549715(CHEMBL4760680)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072081(CHEMBL3407922)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072077(CHEMBL3407866)
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072079(CHEMBL3407913)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549700(CHEMBL4740126)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549711(CHEMBL4764672)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50072080(CHEMBL3407919)
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549705(CHEMBL4756311)
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549712(CHEMBL4790147)
Affinity DataIC50: 29nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549708(CHEMBL4776854)
Affinity DataIC50: 29nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549719(CHEMBL4762842)
Affinity DataIC50: 32nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549701(CHEMBL4745247)
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549709(CHEMBL4743950)
Affinity DataIC50: 37nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549710(CHEMBL4745015)
Affinity DataIC50: 47nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549716(CHEMBL4749459)
Affinity DataIC50: 83nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50061916(3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549713(CHEMBL4790669)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549721(CHEMBL4791546)
Affinity DataIC50: 101nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549718(CHEMBL4784999)
Affinity DataIC50: 118nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549720(CHEMBL4763938)
Affinity DataIC50: 402nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549717(CHEMBL4751196)
Affinity DataIC50: 546nMAssay Description:Inhibition of mouse liver mitochondrial KMO by measuring the 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50061907(meta-nitrobenzoyl)alanine | 2-Amino-4-(3-nitro-phe...)
Affinity DataIC50: 900nMAssay Description:Inhibition of mouse KMOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50061916(3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50549702(CHEMBL4752276)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse liver mitochondrial KMO using kynurenine as substrate by measuring the 3-HK formation preincubated for 5 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50088520(CHEMBL3526575)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50088518(CHEMBL3526576)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Mouse)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50088519(CHEMBL3526743)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed