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Report error Found 178 for UniProtKB: Q8TAF3
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of human USP1/UAF1 in human H1299 cells assessed as reduction in colony formation after 7 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707434(US20240409538, Example 38)
Affinity DataIC50: 5.44nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707433(US20240409538, Example 37)
Affinity DataIC50: 9.53nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707417(US20240409538, Example 18)
Affinity DataIC50: 11.2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707423(US20240409538, Example 25)
Affinity DataIC50: 11.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707422(US20240409538, Example 24)
Affinity DataIC50: 11.8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707416(US20240409538, Example 16)
Affinity DataIC50: 15.8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707419(US20240409538, Example 21)
Affinity DataIC50: 16.1nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 17nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707415(US20240409538, Example 15)
Affinity DataIC50: 17.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707435(US20240409538, Example 39)
Affinity DataIC50: 18.8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707436(US20240409538, Example 40)
Affinity DataIC50: 19.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707426(US20240409538, Example 28)
Affinity DataIC50: 26nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707414(US20240409538, Example 14)
Affinity DataIC50: 30.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352028(US9802904, 89)
Affinity DataIC50: 34nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707437(US20240409538, Example 41)
Affinity DataIC50: 34.2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707427(US20240409538, Example 29)
Affinity DataIC50: 34.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707439(US20240409538, Example 43)
Affinity DataIC50: 38.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707412(US20240409538, Example 5)
Affinity DataIC50: 39.1nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707424(US20240409538, Example 26)
Affinity DataIC50: 39.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707428(US20240409538, Example 30)
Affinity DataIC50: 41.4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM350387(US9802904, 60)
Affinity DataIC50: 43nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352011(US9802904, 72)
Affinity DataIC50: 43nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352013(US9802904, 74)
Affinity DataIC50: 48nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM352011(US9802904, 72)
Affinity DataIC50: 50nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707429(US20240409538, Example 31)
Affinity DataIC50: 57.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM351737(US9802904, 61)
Affinity DataIC50: 61nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352018(US9802904, 79)
Affinity DataIC50: 61nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM352025(US9802904, 86)
Affinity DataIC50: 61nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707411(US20240409538, Example 4)
Affinity DataIC50: 66.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM350386(US9802904, 59)
Affinity DataIC50: 68nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM352025(US9802904, 86)
Affinity DataIC50: 70nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50497350(CHEMBL3187668)
Affinity DataIC50: 70nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 76nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 76nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707425(US20240409538, Example 27)
Affinity DataIC50: 77.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707440(US20240409538, Example 44)
Affinity DataIC50: 78.3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50497334(CHEMBL3182908)
Affinity DataIC50: 80nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM352013(US9802904, 74)
Affinity DataIC50: 80nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM352018(US9802904, 79)
Affinity DataIC50: 80nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM351922(US9802904, 64)
Affinity DataIC50: 86nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM352014(US9802904, 75)
Affinity DataIC50: 90nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707431(US20240409538, Example 33)
Affinity DataIC50: 94.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707441(US20240409538, Example 45)
Affinity DataIC50: 99.7nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50069762(CHEMBL3182437 | ML323 | US9802904, 87)
Affinity DataIC50: 100nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50497315(CHEMBL3188490)
Affinity DataIC50: 110nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50497335(CHEMBL3181906)
Affinity DataIC50: 110nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50497363(CHEMBL3189120)
Affinity DataIC50: 110nMAssay Description:Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM707430(US20240409538, Example 32)
Affinity DataIC50: 111nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandPNGBDBM350377(US9802904, 51)
Affinity DataIC50: 120nMAssay Description:This example demonstrates reversible inhibition of USP1/UAF1 by an embodiment of the invention.The compound (81) at a concentration of ten times its ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

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