Compile Data Set for Download or QSAR
Report error Found 1536 of affinity data for UniProtKB/TrEMBL: Q8IXJ6
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29041(cambinol analog, 6a)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29043(cambinol analog, 6c)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29044(cambinol analog, 6d)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29045(cambinol analog, 6i)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29046(cambinol analog, 6ii)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29047(cambinol analog, 6iii)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29048(cambinol analog, 6iv)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29049(cambinol analog, 6v)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29050(cambinol analog, 6vi)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29052(cambinol analog, 6viii)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29053(cambinol analog, 6ix)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29054(cambinol analog, 6x)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM29055(cambinol analog, 6xi)
Affinity DataAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataEC50:  160nMAssay Description:Activation of human SirT2 protein fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50428988(CHEMBL2333666)
Affinity DataEC50:  1.16E+4nMAssay Description:Activation of at N-terminal GST-tagged SIRT2 (34 to 356 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM31963(carbohydrazide derivative, 5f)
Affinity DataEC50:  1.65E+4nMAssay Description:Activation of at N-terminal GST-tagged SIRT2 (34 to 356 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50376978(SRT-2183 | CHEMBL403308)
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50228364(3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imi...)
Affinity DataEC50: >3.00E+5nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50228363(N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazo...)
Affinity DataEC50:  3.70E+4nMAssay Description:Activation of SIRT2 by mass spectrometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576692(CHEMBL4872768)
Affinity DataKd:  3.90E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576693(CHEMBL4866103)
Affinity DataKd:  3.30E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576694(CHEMBL4860443)
Affinity DataKd:  3.20E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576695(CHEMBL4864110)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576701(CHEMBL4867959)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576688(CHEMBL4873020)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576689(CHEMBL4872893)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576709(CHEMBL4847877)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50576690(CHEMBL4873772)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50148829(CHEMBL3769432)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431093(CHEMBL2338810)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431121(CHEMBL2332037)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431118(CHEMBL2332041)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431097(CHEMBL2332039)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50152093(CHEMBL3779989)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431117(CHEMBL2332042)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431119(CHEMBL2332040)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431115(CHEMBL2332044)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431116(CHEMBL2332043)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50502269(CHEMBL4446458)
Affinity DataIC50: 7nMAssay Description:Inhibition of 5-(3-((1r,4r)-4-((5S,8S,11S,14S,17S,20S,29S)-11-((1H-imidazol-4-yl)methyl)-1,33-diamino-5-carbamoyl-17-(4-(4-(4-((4-(dimethylamino)phen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50152068(CHEMBL3781485)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant His6 tagged human SIRT2 using 0.39 mM H2N-HK-[N(epsilon)-acetyl-lysine]-LM-COOH as substrate measured after 12 mins HPLC an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431096(CHEMBL2332055)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431120(CHEMBL2332038)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50152068(CHEMBL3781485)
Affinity DataIC50: 10nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50168494(CHEMBL3805001)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50168735(CHEMBL3805929)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431095(CHEMBL2338808)
Affinity DataIC50: 16nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50168905(CHEMBL3805692)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50431094(CHEMBL2338809)
Affinity DataIC50: 17nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

LigandPNGBDBM50168488(CHEMBL3804834)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2017
Entry Details Article
PubMed
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