Compile Data Set for Download or QSAR
Report error Found 14 of affinity data for UniProtKB/TrEMBL: Q8HZ64
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022723((2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+...)
Affinity DataEC50:  1.01E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359499(METHAMPHETAMINE | (S)Methamphetamine)
Affinity DataEC50:  5.30E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  2.50E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50022721((R)-amphetamine | CHEMBL19393 | AMPHETAMINE)
Affinity DataEC50:  1.86E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359501(CHEMBL1927024 | HYDROXYAMPHETAMINE)
Affinity DataEC50:  101nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359502(CHEMBL1230845 | HYDROXYAMPHETAMINE)
Affinity DataEC50:  424nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86238(NSC_3050061 | CAS_3050061 | MDA,S(+))
Affinity DataEC50:  1.35E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86239(NSC_3046161 | CAS_3046161 | MDA,R(-))
Affinity DataEC50:  2.48E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM85332(MDMA, R(-))
Affinity DataEC50:  1.61E+4nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86234(NSC_126235 | CAS_64057-70-1 | MDMA,S(+))
Affinity DataEC50:  7.40E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359503(CHEMBL1927026)
Affinity DataEC50:  3.30E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50274042((S)-1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine ...)
Affinity DataEC50:  2.14E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064708((R)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataEC50:  1.39E+4nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359506(CHEMBL102594)
Affinity DataEC50:  900nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed