Compile Data Set for Download or QSAR
Report error Found 15 of affinity data for UniProtKB/TrEMBL: Q8CIM5
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataEC50:  4.27E+3nMAssay Description:Agonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239172(CHEMBL4088884)
Affinity DataEC50:  295nMAssay Description:Agonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  26nMAssay Description:Agonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239172(CHEMBL4088884)
Affinity DataEC50:  178nMAssay Description:Agonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  13nMAssay Description:Agonist activity at GPR84 in mouse bone-marrow-derived neutrophils assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239172(CHEMBL4088884)
Affinity DataEC50:  2.88E+3nMAssay Description:Agonist activity at GPR84 in mouse bone-marrow-derived neutrophils assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50548393(CHEMBL3716446)
Affinity DataIC50: 39nMAssay Description:Inverse agonist activity at recombinant mouse GPR84 receptor expressed in HEK293 cells co-expressing GNAO1 transcription variant 1 assessed as reduct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in PSB-16671-induced stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in ZQ-16-induced stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 145nMAssay Description:Antagonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as reduction in PSB-16671-induced stimulation of [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50603895(CHEMBL5179395)
Affinity DataIC50: 273nMAssay Description:Antagonist activity at mouse GPR84 expressed in HEK293 cells assessed as reduction in 6-OAU induced intracellular calcium response preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50556779(CHEMBL3715656)
Affinity DataIC50: 316nMAssay Description:Antagonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as reduction in ZQ-16-induced stimulation of [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50603869(CHEMBL5194984)
Affinity DataIC50: 454nMAssay Description:Antagonist activity at mouse GPR84 expressed in HEK293 cells assessed as reduction in 6-OAU induced intracellular calcium response preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetG-protein coupled receptor 84(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50548412(CHEMBL4776061)
Affinity DataIC50: 636nMAssay Description:Inverse agonist activity at recombinant mouse GPR84 receptor expressed in HEK293 cells co-expressing GNAO1 transcription variant 1 assessed as reduct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed