Compile Data Set for Download or QSAR
Report error Found 7 of affinity data for UniProtKB/TrEMBL: Q8CI15
TargetSphingosine kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50438142(CHEMBL2409847)
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse SphK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSphingosine kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50438143(CHEMBL2409891)
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse SphK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSphingosine kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50041978(CHEMBL3134157)
Affinity DataKi:  3.60nMAssay Description:Inhibition of SphK1 in mouse erythrocytes using sphingosine as substrate by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetSphingosine kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50266437(CHEMBL4092871)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant mouse SPHK1 using sphingosine as substrate in presence ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details Article
PubMed
TargetSphingosine kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50514480(CHEMBL4466524)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of recombinant mouse SphK1 expressed in baculovirus infected Sf9 insect cells using D-erythro-sphingosine as substrate measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetSphingosine kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50407506(CHEMBL4595333)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of recombinant mouse SphK1 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine and [gamma-32P]ATP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingosine kinase 1(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50407507(CHEMBL5281819)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of recombinant mouse SphK1 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine and [gamma-32P]ATP as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed