Compile Data Set for Download or QSAR
Report error Found 3 of affinity data for UniProtKB/TrEMBL: Q6S996
TargetPhosphodiesterase(Leishmania major)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50397078(CHEMBL2171452)
Affinity DataIC50: 130nMAssay Description:Inhibition of Leishmania major recombinant PDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPhosphodiesterase(Leishmania major)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of Leishmania major PDEB1 catalytic domain (582 to 940 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP or [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPhosphodiesterase(Leishmania major)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of Leishmania major PDEB1 catalytic domain (582 to 940 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP or [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed