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Report error Found 3227 of affinity data for UniProtKB/TrEMBL: Q64663
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CHEMBL69234 | CAS_149017-66-3 | NSC_6093163 | PPAD...)
Affinity DataEC50:  6.20E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118235(Brilliant Blue | CHEMBL423337)
Affinity DataEC50:  400nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 7 (P2X7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254322(US9464084, 222 | US10112937, Example 222 | US10150...)
Affinity DataIC50: 1nMpH: 7.4Assay Description:1321 N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254322(US9464084, 222 | US10112937, Example 222 | US10150...)
Affinity DataIC50: 1nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254322(US9464084, 222 | US10112937, Example 222 | US10150...)
Affinity DataIC50: 1nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254322(US9464084, 222 | US10112937, Example 222 | US10150...)
Affinity DataIC50: 1nMAssay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254322(US9464084, 222 | US10112937, Example 222 | US10150...)
Affinity DataIC50: 1nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM296261(US10112937, Example 351)
Affinity DataIC50: 1.30nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM174795(US9102686, 26 | US9540388, 26 | US10053462, 26)
Affinity DataIC50: 1.40nMpH: 7.4Assay Description:Ca.sup.2+flux: 1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
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TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254234(US9464084, 119 | US10112937, Example 119 | US10150...)
Affinity DataIC50: 1.5nMpH: 7.4Assay Description:1321 N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254234(US9464084, 119 | US10112937, Example 119 | US10150...)
Affinity DataIC50: 1.5nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254234(US9464084, 119 | US10112937, Example 119 | US10150...)
Affinity DataIC50: 1.5nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254234(US9464084, 119 | US10112937, Example 119 | US10150...)
Affinity DataIC50: 1.5nMAssay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254266(US9464084, 158 | US10112937, Example 158 | US10150...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at recombinant rat P2X7 expressed in human 1321N1 cells assessed as inhibition of BzATP-induced calcium flux preincubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254234(US9464084, 119 | US10112937, Example 119 | US10150...)
Affinity DataIC50: 1.5nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254234(US9464084, 119 | US10112937, Example 119 | US10150...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at recombinant rat P2X7 receptor expressed in 1321N1 cells measured after 30 mins by fluorescence based calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254314(US9464084, 212 | US10112937, Example 212 | US10150...)
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:1321 N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254314(US9464084, 212 | US10112937, Example 212 | US10150...)
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254314(US9464084, 212 | US10112937, Example 212 | US10150...)
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM296301(US10112937, Example 404)
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254314(US9464084, 212 | US10112937, Example 212 | US10150...)
Affinity DataIC50: 1.60nMAssay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254314(US9464084, 212 | US10112937, Example 212 | US10150...)
Affinity DataIC50: 1.60nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254233(US9464084, 118 | US10112937, Example 118 | US10150...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at rat recombinant P2X7 expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization after 30 mins by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254317(US9464084, 215 | US10112937, Example 215 | US10150...)
Affinity DataIC50: 1.90nMpH: 7.4Assay Description:1321 N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254317(US9464084, 215 | US10112937, Example 215 | US10150...)
Affinity DataIC50: 1.90nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254317(US9464084, 215 | US10112937, Example 215 | US10150...)
Affinity DataIC50: 1.90nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254317(US9464084, 215 | US10112937, Example 215 | US10150...)
Affinity DataIC50: 1.90nMAssay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM296301(US10112937, Example 404)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at rat recombinant P2X7 expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization after 30 mins by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254317(US9464084, 215 | US10112937, Example 215 | US10150...)
Affinity DataIC50: 1.90nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254203(US9464084, 88 | US10112937, Example 88 | US1015076...)
Affinity DataIC50: 2nMpH: 7.4Assay Description:1321 N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254203(US9464084, 88 | US10112937, Example 88 | US1015076...)
Affinity DataIC50: 2nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254203(US9464084, 88 | US10112937, Example 88 | US1015076...)
Affinity DataIC50: 2nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254203(US9464084, 88 | US10112937, Example 88 | US1015076...)
Affinity DataIC50: 2nMAssay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254203(US9464084, 88 | US10112937, Example 88 | US1015076...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at recombinant rat P2X7 expressed in human 1321N1 cells assessed as inhibition of BzATP-induced calcium flux preincubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2020
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254203(US9464084, 88 | US10112937, Example 88 | US1015076...)
Affinity DataIC50: 2nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254203(US9464084, 88 | US10112937, Example 88 | US1015076...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at recombinant rat P2X7 receptor expressed in 1321N1 cells measured after 30 mins by fluorescence based calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254311(US9464084, 209 | US10112937, Example 209 | US10150...)
Affinity DataIC50: 2.10nMpH: 7.4Assay Description:1321 N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254311(US9464084, 209 | US10112937, Example 209 | US10150...)
Affinity DataIC50: 2.10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254311(US9464084, 209 | US10112937, Example 209 | US10150...)
Affinity DataIC50: 2.10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254311(US9464084, 209 | US10112937, Example 209 | US10150...)
Affinity DataIC50: 2.10nMAssay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254314(US9464084, 212 | US10112937, Example 212 | US10150...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at rat recombinant P2X7 expressed in 1321N1 cells assessed as inhibition of BzATP-induced calcium mobilization after 30 mins by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM254311(US9464084, 209 | US10112937, Example 209 | US10150...)
Affinity DataIC50: 2.10nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM296257(US10112937, Example 346)
Affinity DataIC50: 2.20nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM296259(US10112937, Example 349)
Affinity DataIC50: 2.20nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM173353(US9096596, 71 | US9604982, Example 71 | US10323032...)
Affinity DataIC50: 2.40nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high gluc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM173353(US9096596, 71 | US9604982, Example 71 | US10323032...)
Affinity DataIC50: 2.40nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM173353(US9096596, 71 | US9604982, Example 71 | US10323032...)
Affinity DataIC50: 2.40nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM173353(US9096596, 71 | US9604982, Example 71 | US10323032...)
Affinity DataIC50: 2.40nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50587051(CHEMBL5086274)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at rat P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium-flux measured after 60 mins by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM173345(US9096596, 63 | US9604982, Example 63 | US10323032...)
Affinity DataIC50: 2.5nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high gluc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

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