Compile Data Set for Download or QSAR
Report error Found 142 of affinity data for UniProtKB/TrEMBL: Q63707
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50018008(CHEMBL3289671 | US9238653, Table 5, Compound 43)
Affinity DataKd:  48nMAssay Description:Binding affinity to rat DHODH by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054585((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054556((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054573((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054601(5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM14712(A77 1726 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4...)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against rat dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054541((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054590((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054552((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-methylsul...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM14712(A77 1726 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054560((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054581((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-trifluoro...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054597((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(5-trifluoro...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat DHODH (amino acid residues 30 to 396) expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054574((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(3-methyl-4-...)
Affinity DataIC50: 18nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM14712(A77 1726 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4...)
Affinity DataIC50: 20nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM14712(A77 1726 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4...)
Affinity DataIC50: 20nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM29024(CHEMBL141732 | cyanocyclopropylpropenamide, 4)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM29024(CHEMBL141732 | cyanocyclopropylpropenamide, 4)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054557((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-nitro-phe...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054600(2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)pen...)
Affinity DataIC50: 23nMAssay Description:Inhibition of rat DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054600(2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)pen...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM14712(A77 1726 | CHEMBL973 | (2Z)-2-cyano-3-hydroxy-N-[4...)
Affinity DataIC50: 26nMAssay Description:Inhibition of rat dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054553((Z)-2-Cyano-N-(4-cyano-3-methyl-phenyl)-3-cyclopro...)
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 33nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054594((Z)-N-(4-Chloro-3-methyl-phenyl)-2-cyano-3-cyclopr...)
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054549((Z)-N-(5-Bromo-pyridin-2-yl)-2-cyano-3-cyclopropyl...)
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054564((Z)-2-Cyano-3-cyclopropyl-N-(3-ethyl-4-trifluorome...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50407985(CHEMBL2111978)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50018006(CHEMBL3289672 | US9238653, Table 5, Compound 49)
Affinity DataIC50: 49nMAssay Description:Inhibition of rat DHODH (amino acid residues 30 to 396) expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50363564(CHEMBL1946851)
Affinity DataIC50: 50nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054578((Z)-N-(4-Bromo-3-methyl-phenyl)-2-cyano-3-cyclopro...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054587(Alpha-cyano-beta-hydroxy enamide, 6 | CHEMBL141195...)
Affinity DataIC50: 53nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054584((Z)-N-(4-Chloro-phenyl)-2-cyano-3-cyclopropyl-3-hy...)
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50363559(CHEMBL1946659)
Affinity DataIC50: 66nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054606((Z)-N-(4-Acetyl-phenyl)-2-cyano-3-cyclopropyl-3-hy...)
Affinity DataIC50: 68nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054555((Z)-N-(5-Chloro-pyridin-2-yl)-2-cyano-3-cyclopropy...)
Affinity DataIC50: 76nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against rat dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054548((Z)-N-(4-Bromo-phenyl)-2-cyano-3-cyclopropyl-3-hyd...)
Affinity DataIC50: 79nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054591((Z)-N-(3-Chloro-4-methyl-phenyl)-2-cyano-3-cyclopr...)
Affinity DataIC50: 79nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054565(CHEMBL141472 | CHEMBL344613 | (2Z,4E)-2-Cyano-3-hy...)
Affinity DataIC50: 107nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50363563(CHEMBL1946850)
Affinity DataIC50: 120nMAssay Description:Inhibition of dihydroorotate dehydrogenase in Wistar rat liver mitochondrial/microsomal membranes measured for 5 mins by 2,6-dichlorophenolindophenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 127nMpH: 8.0 T: 2°CAssay Description:To determine the inhibitory potency of the drugs, the initial velocity of the DHODR-catalyzed reaction at saturating concentrations of DHO (1 mM) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 127nMAssay Description:Inhibition of rat recombinant His-tagged truncated DHODH expressed in Escherichia coli using dihydroorotate as substrate by chromogen reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50018008(CHEMBL3289671 | US9238653, Table 5, Compound 43)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat DHODH (amino acid residues 30 to 396) expressed in Escherichia coli BL21 cells assessed as orotic acid production using dihydroorot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50598923(CHEMBL5193821)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054589((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-phenethyl...)
Affinity DataIC50: 138nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054579((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-methanesu...)
Affinity DataIC50: 158nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
University of Texas At Dallas

Curated by ChEMBL
LigandPNGBDBM50054545(4-((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-acryloylami...)
Affinity DataIC50: 158nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
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