Compile Data Set for Download or QSAR
Report error Found 46 of affinity data for UniProtKB/TrEMBL: Q63704
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403039(CHEMBL2216778)
Affinity DataIC50: 30nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403029(CHEMBL2216792)
Affinity DataIC50: 40nMAssay Description:Inhibition of rat CPT1B expressed in intact Saccharomyces cerevisiae using [methyl-3H]carnitine by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403040(CHEMBL2216779)
Affinity DataIC50: 55nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403037(CHEMBL2216774)
Affinity DataIC50: 130nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403041(CHEMBL2216776)
Affinity DataIC50: 150nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403038(CHEMBL2216777)
Affinity DataIC50: 180nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260111(CHEBI:15531 | MALONYL-COENZYME A)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM80613(SMR000674573 | cid_9926449 | 1-(2,3,4-Trimethoxy-b...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CPT1A in rat myocardiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 1.45E+3nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101594([3-Carboxy-2-(decane-1-sulfonylamino)-propyl]-trim...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101598([3-Carboxy-2-(dodecane-1-sulfonylamino)-propyl]-tr...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101604([3-Carboxy-2-(dodecane-1-sulfonylamino)-propyl]-tr...)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101589([3-Carboxy-2-(nonylaminosulphonyl-amino)-propyl]-t...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101591([3-Carboxy-2-(undecylaminosulphonyl-amino)-propyl]...)
Affinity DataIC50: 5.80E+3nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101591([3-Carboxy-2-(undecylaminosulphonyl-amino)-propyl]...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101598([3-Carboxy-2-(dodecane-1-sulfonylamino)-propyl]-tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101600([3-Carboxy-2-(undecylaminosulphonyl-amino)-propyl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101604([3-Carboxy-2-(dodecane-1-sulfonylamino)-propyl]-tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101600([3-Carboxy-2-(undecylaminosulphonyl-amino)-propyl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM61402(perhexiline maleate | (Z)-but-2-enedioic acid;2-(2...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260115(CHEMBL4097976)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260105(CHEMBL1592481)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Wistar rat heart mitochondrial CPT-1 assessed as reduction in conversion of palmitoyl CoA and L-carnitine into palmitoylcarnitine prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260109(CHEMBL4077250)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50403034(CHEMBL2114397)
Affinity DataIC50: 2.73E+4nMAssay Description:Maximal inhibition of rat CPT1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260108(CHEMBL4082420)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122839([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 4.34E+4nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260104(CHEMBL4081530)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122827([3-Carboxy-2-(3-nonyl-ureido)-propyl]-trimethyl-am...)
Affinity DataIC50: 4.62E+4nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260105(CHEMBL1592481)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122833((3-Carboxy-2-octyloxycarbonylamino-propyl)-trimeth...)
Affinity DataIC50: 8.01E+4nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101590([3-Carboxy-2-(3-nonyl-ureido)-propyl]-trimethyl-am...)
Affinity DataIC50: 8.32E+4nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260112(CHEMBL4068222)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122828([3-Carboxy-2-(3-undecyl-ureido)-propyl]-trimethyl-...)
Affinity DataIC50: 1.18E+5nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122834([3-Carboxy-2-(3-dodecyl-ureido)-propyl]-trimethyl-...)
Affinity DataIC50: 1.20E+5nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122836([3-Carboxy-2-(3-tetradecyl-ureido)-propyl]-trimeth...)
Affinity DataIC50: 1.67E+5nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50101593((3-Carboxy-2-octyloxycarbonylamino-propyl)-trimeth...)
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]palmitoyl-CoA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260113(CHEMBL4059578)
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122837([3-Carboxy-2-(3-heptyl-ureido)-propyl]-trimethyl-a...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122835([3-Carboxy-2-(3-nonyl-ureido)-propyl]-trimethyl-am...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50122829((3-Carboxy-2-octyloxycarbonylamino-propyl)-trimeth...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260114(CHEMBL4079982)
Affinity DataIC50: 4.75E+5nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50260110(CHEMBL4097557)
Affinity DataIC50: 7.15E+5nMAssay Description:Inhibition of rat heart mitochondrial CPT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2020
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50046145(2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4...)
Affinity DataKi:  2.80E+3nMAssay Description:Compound was evaluated for its ability to inhibit carnitine palmitoyltransferase I activity in intact mitochondria from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037268((3R)-3-hydroxy-4-(trimethylammonio)butanoate | (-)...)
Affinity DataKi:  1.00E+5nMAssay Description:Tested against neonatal rat cardiac myocyte carnitine palmitoyltransferase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037262((R)-3-Hydroxy-5,5-dimethyl-hexanoic acid anion)
Affinity DataKi:  1.40E+6nMAssay Description:Tested against neonatal rat cardiac myocyte carnitine palmitoyltransferase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetCarnitine O-palmitoyltransferase 1, muscle isoform(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037261(3-Hydroxy-5,5-dimethyl-hexanoic acid anion)
Affinity DataKi:  3.60E+6nMAssay Description:Tested against neonatal rat cardiac myocyte carnitine palmitoyltransferase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed