Compile Data Set for Download or QSAR
Report error Found 444 for UniProtKB: Q62758
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50155152(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Affinity DataEC50:  538nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50449570(CHEMBL2448137)
Affinity DataEC50:  3.87E+3nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50181836(CHEMBL319673 | 4-amino-N-1-azatricyclo[3.3.1.0~3,7...)
Affinity DataEC50:  51nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289989(4-Amino-N-(3-aza-tricyclo[3.3.1.0*3,7*]non-9-yl)-5...)
Affinity DataEC50:  382nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289990(4-Amino-N-(3-aza-tricyclo[3.3.1.0*3,7*]non-9-ylmet...)
Affinity DataEC50:  660nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  17nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288594(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataEC50:  4.5nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288590(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataEC50:  11nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288591(2-(2,3-dihydrobenzo[b]furan-7-ylcarboxamido)-(2S)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288585(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataEC50:  7.40nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288596(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataEC50:  19nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50398590(CHEMBL2179583)
Affinity DataEC50:  0.960nMAssay Description:Agonist activity at rat 5HT4L receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at rat 5HT4L receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50398598(CHEMBL2152922)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at rat 5HT4L receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at rat 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50398590(CHEMBL2179583)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at rat 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at rat 5HT4S receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50398598(CHEMBL2152922)
Affinity DataEC50:  0.620nMAssay Description:Agonist activity at rat 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50449568(CHEMBL2448558)
Affinity DataEC50:  98nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataEC50:  66nMAssay Description:Tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assay of racemate mixtureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50122874(SC-53116 | 4-Amino-5-chloro-2-methoxy-N-((1S,7aS)-...)
Affinity DataEC50:  449nMAssay Description:Tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assay of racemate mixtureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142919(CHEMBL3759860)
Affinity DataEC50:  46nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142920(CHEMBL3759944)
Affinity DataEC50:  100nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataEC50:  102nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142915(CHEMBL3758932)
Affinity DataEC50:  676nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142914(CHEMBL3758199)
Affinity DataEC50:  251nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142913(CHEMBL3759601)
Affinity DataEC50:  708nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142910(CHEMBL3758945)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142909(CHEMBL3759928)
Affinity DataEC50:  6.03E+3nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142907(CHEMBL3759259)
Affinity DataEC50:  380nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50142906(CHEMBL3759348)
Affinity DataEC50:  1.55E+3nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289985(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-5-ylmet...)
Affinity DataEC50:  217nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289987(4-Acetylamino-N-(3-aza-tricyclo[3.3.1.0*3,7*]non-9...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289988(4-Acetylamino-N-(3-aza-tricyclo[3.3.1.0*3,7*]non-9...)
Affinity DataEC50:  3.34E+3nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataEC50:  51nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289991(4-Amino-N-[2-(1-aza-tricyclo[3.3.1.0*3,7*]non-5-yl...)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity against serotonin 5-HT4 receptor in rat tunica muscularis mucosae assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288586(2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylc...)
Affinity DataEC50:  195nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288587(2-(4-amino-5-chloro-2,3-dihydrobenzo[b]furan-7-ylc...)
Affinity DataEC50:  19nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288595(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataEC50:  1.90nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50288597(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataEC50:  2nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataEC50:  56nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataEC50:  55nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50056419(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataEC50:  203nMAssay Description:Compound was evaluated for the agonistic activity towards 5-hydroxytryptamine 4 receptor using the rat tunica muscularis mucosae (TMM) esophagus stri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataEC50:  23nMAssay Description:Compound was tested for agonist activity at the 5-hydroxytryptamine 4 receptor in the rat tunica muscularis mucosae (TMM) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50122873(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataEC50:  40.3nMAssay Description:Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataEC50:  23.7nMAssay Description:Efficient 5-hydroxytryptamine 4 agonist in the rat tunica muscularis mucosaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataEC50:  55nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50181844((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 4-amin...)
Affinity DataEC50:  1.5nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50181838(4-amino-5-chloro-2-ethoxy-N-[(1S,7aS)-hexahydro-1H...)
Affinity DataEC50:  195nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50181839(N-exo-((4S,7alphaS)-tetrahydro-1H-pyrrolizin-4(5H)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 444 total ) | Next | Last >>
Jump to: