Compile Data Set for Download or QSAR
Report error Found 31 of affinity data for UniProtKB/TrEMBL: Q61614
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50034267(PD156707 | PD-156707 | CHEMBL8981 | 3-Benzo[1,3]di...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281579((S)-3-{2-[((R)-2-Acetylamino-3-phenyl-propionyl)-b...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281576((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281577((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(4-hydroxy-pheny...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281586((R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propiony...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281580((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 57nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281581((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 70nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281582((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 75nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281575((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 77nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281585((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 79nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281587((S)-3-[(R)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 98nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281583((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 114nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281910((S)-3-[(S)-5-((S)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 230nMAssay Description:Binding affinity for Endothelin A receptor was determined in murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281584((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 230nMAssay Description:The compound was tested for the binding affinity against eEndothelin A receptor in murine 3T3 cells using [125I]ET1 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281911((R)-3-[(R)-5-((S)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 250nMAssay Description:Binding affinity for Endothelin A receptor was determined in murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281578((S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 270nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50281912((S)-3-[(R)-5-((S)-2-Acetylamino-3-phenyl-propionyl...)
Affinity DataIC50: 900nMAssay Description:Binding affinity for Endothelin A receptor was determined in murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50304494(3-Benzo[1,3]dioxol-5-yl-4-[3-(2-bromoethoxy)-4,5-d...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50304495(2-{4-[4-(Benzo[1,3]dioxol-5-yl)-2-hydroxy-5-oxo-3-...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50304496(3-Benzo[1,3]dioxol-5-yl-4-[3-(2-fluoroethoxy)-4,5-...)
Affinity DataKi:  1.09nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50304496(3-Benzo[1,3]dioxol-5-yl-4-[3-(2-fluoroethoxy)-4,5-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50304497(2-(5-{[4-(Benzo[1,3]dioxol-5-yl)-2-hydroxy-2-(4-me...)
Affinity DataKi:  1.26nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50336694(3-Benzo[1,3]dioxol-5-yl-4-{3-(2-(2-(2-(2-fluoroeth...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50336695(3-Benzo[1,3]dioxol-5-yl-4-{3-[1-(2-{2-[2-(2-fluoro...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50304498(3-Benzo[1,3]dioxol-5-yl-5-[4-(2-fluoroethoxy)pheny...)
Affinity DataKi:  2.43nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50336697(3-Benzo[1,3]dioxol-5-yl-4-[3-(2-{2-[2-(2-{4-[4-(2-...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50336699(N-[1-(2-{2-[2-(2-{5-[4-Benzo[1,3]dioxol-5-yl-2-hyd...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50336696(3-Benzo[1,3]dioxol-5-yl-4-[3-(2-{2-[2-(2-{1-[2-(2-...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50336698(N-[1-(2-{2-[2-(2-{5-[4-Benzo[1,3]dioxol-5-yl-2-hyd...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50336700(3-Benzo[1,3]dioxol-5-yl-4-{3-[2-(2-{2-[2-(4-fluoro...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Mouse)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50304499(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-[4-(2-bromoeth...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed