Compile Data Set for Download or QSAR
Report error Found 65 of affinity data for UniProtKB/TrEMBL: Q53I59
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50: 230nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50020875(1-Ethyl-4-(N'-isopropylidene-hydrazino)-1H-pyrazol...)
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273546(1-(3,4-Bisdifluoromethoxyphenyl)-3-phenylpropan-1-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336543(5-(4-chlorophenyl)-3-((pyridin-2-ylsulfonyl)methyl...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273544(1-[4-Difluoromethoxy-3-(tetrahydrofuran-3-yloxy)ph...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273574(2-Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofur...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273548(1-(3,4-Bisdifluoromethoxyphenyl)-4-phenylbutan-1-o...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273984(4-(2-Methoxy-4-pentanoylphenoxy)piperidine-1-carbo...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273575(1-[4-Difluoromethoxy-3-(tetrahydrofuran-3-yloxy)ph...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273572(1-(3-Cyclopentyloxy-4-difluoromethoxyphenyl]-3-met...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336542(3-(1-(3-methoxy-4-(pyridin-2-yloxy)phenyl)butyl)qu...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273987(1-[3-Methoxy-4-(tetrahydropyran-4-yloxy)phenyl]pen...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273510(1-[4-Difluoromethoxy-3-(pyridin-2-yloxy)phenyl]but...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336541(ethyl 2-(2-(3-(3,4-dichlorophenyl)ureido)thiazol-4...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336540(2-((furan-2-ylmethylsulfonyl)methyl)-4-phenylthiaz...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataIC50: 3.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336539(1-(4-(difluoromethoxy)-3-(pyridin-2-yloxy)phenyl)-...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273985(1-[3-Methoxy-4-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336538(2-((2-(thiophen-2-yl)thiazol-4-yl)methyl)isoindoli...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336537(N-benzyl-5-(4-cyano-3-(methylthio)isoxazol-5-yl)th...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336536(3-((furan-2-ylmethylsulfonyl)methyl)-5-(isoxazol-5...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336535(ethyl 2,5-dimethyl-6-(5-phenyl-4H-1,2,4-triazol-3-...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273511(1-[4-Difluoromethoxy-3-(tetrahydropyran-4-yloxy)ph...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273508(2-Cyclohexyl-1-[4-methoxy-3-(tetrahydrofuran-3-ylo...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273331(1-[3-Methoxy-4-(tetrahydrofuran-3-yloxy)phenyl]pen...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273543(Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofuran...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273547(1-(3,4-Bisdifluoromethoxyphenyl)-2-cyclohexylethan...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM39098(2-(1,3-benzothiazol-2-ylmethyl)-1,1-dioxo-1,2-benz...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273988(1-[3-Methoxy-4-(tetrahydrofuran-3-yloxy)phenyl]but...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336534(N'-(6-tert-butylthieno[3,2-d]pyrimidin-4-yl)thioph...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273986(4-(4-Butyryl-2-methoxyphenoxy)piperidine-1-carboxy...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataIC50: 6.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336533(3-allyl-7-(5-(furan-2-yl)-1,3,4-oxadiazol-2-ylthio...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50273335(1-[4-Methoxy-3-(tetrahydrofuran-3-yloxy)phenyl]but...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336515((E)-N'-(pyridin-4-ylmethylene)-2-(5-(pyrrolidin-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336516(5-((4-chlorophenylthio)methyl)-3-((pyridin-2-ylsul...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336517(1-cyclopentyl-3-(4-(piperidin-1-ylsulfonyl)phenyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336518(3-((4-fluorophenylsulfonyl)methyl)-5-(thiophen-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336519(3-(4-chlorophenylthio)-1-(pyridin-4-ylmethyl)pyrro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336520(2-(2-(4-chlorophenyl)-2-oxoethylthio)-6-(dimethoxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336521(2-((4-(1,3-dithiolan-2-yl)phenoxy)methyl)thiazole-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336522(2-(indolin-1-yl)-N-(5-(thiophen-2-yl)-2,3-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336523(3-benzyl-N-(2-fluorophenyl)-3H-[1,2,3]triazolo[4,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336524(N-(2-chlorophenyl)-2-(7-chloroquinazolin-4-yloxy)a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336526(1-(benzo[b]thiophen-3-yl)-3-(2,3-dihydro-1H-inden-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336531(4-methoxy-3-(tetrahydrofuran-3-yloxy)benzaldehyde ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336532(1-(4-methoxy-3-(tetrahydro-2H-pyran-4-yloxy)phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336530(1-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)but...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50336529(4-(difluoromethoxy)-3-hydroxybenzaldehyde | CHEMBL...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
Displayed 1 to 50 (of 65 total ) | Next | Last >>
Jump to: