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Report error Found 34 of affinity data for UniProtKB/TrEMBL: Q27743
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23229([(4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]car...)
Affinity DataIC50: 1.75E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataIC50: 2.64E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23227([(4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]car...)
Affinity DataIC50: 3.13E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23228([(2-cyano-4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)me...)
Affinity DataIC50: 8.25E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23243(4-hydroxy-1,2-oxazole-3-carboxylic acid | 1,2(1,5)...)
Affinity DataIC50: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23250(4-hydroxy-1,2-oxazole-3,5-dicarboxylic acid | 1,2(...)
Affinity DataIC50: 8.10E+4nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23224(7-{[4-(formamidoformic acid)-3-methoxyphenyl]metho...)
Affinity DataIC50: 8.73E+4nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23222(carbamoylformic acid | Oxalamic acid | Oxamidic Ac...)
Affinity DataIC50: 9.25E+4nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23258(1H-1,2,3-triazole-5-carboxylic acid | Triazole, TR...)
Affinity DataIC50: 9.80E+4nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23257(2-benzyl-5-hydroxy-2H-1,2,3-triazole-4-carboxylic ...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23256(1-benzyl-4-hydroxy-1H-1,2,3-triazole-5-carboxylic ...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23255(5-hydroxy-2-methyl-2H-1,2,3-triazole-4-carboxylic ...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23254(4-hydroxy-1-methyl-1H-1,2,3-triazole-5-carboxylic ...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23253(4-methoxy-1,2,5-thiadiazole-3-carboxylic acid | 1,...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23252(4-amino-1,2,5-thiadiazole-3-carboxylic acid | 1,2,...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23249(ethyl 5-hydroxy-1,2-oxazole-4-carboxylate | 1,2(1,...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23248(methyl 5-hydroxy-3-methyl-1,2-oxazole-4-carboxylat...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23244(3-hydroxy-5-methyl-1,2-oxazole-4-carboxylic acid |...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23245(2-methyl-3-oxo-2,3-dihydro-1,2-oxazole-4-carboxyli...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23246(3-methoxy-1,2-oxazole-4-carboxylic acid | 1,2(1,5)...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23247(ethyl 3-hydroxy-1,2-oxazole-4-carboxylate | 1,2(1,...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23226(7-{2-[4-(formamidoformic acid)-3-methoxyphenyl]eth...)
Affinity DataIC50: 1.91E+5nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23235(4-[(2-hydroxyethyl)amino]-1,2,5-oxadiazole-3-carbo...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23241(ethyl 4-[(4-methoxyphenyl)methoxy]-1,2,5-oxadiazol...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23240(4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}-1,2,5-oxadiaz...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23239(ethyl 4-hydroxy-1,2,5-oxadiazole-3-carboxylate | 1...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23238((3,4-dichlorophenyl)methyl 4-hydroxy-1,2,5-oxadiaz...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23237(2-(4-hydroxy-1,2,5-oxadiazol-3-yl)acetic acid | 1,...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23236(1,2,5-oxadiazole-3-carboxylic acid | 1,2,5-oxadiaz...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23234(4-amino-1,2,5-oxadiazole-3-carboxylic acid | 1,2,5...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23225(7-{2-[4-(formamidoformic acid)phenyl]ethoxy}-5-hyd...)
Affinity DataIC50: 2.41E+5nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23232(4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | 1,2...)
Affinity DataKi:  210nM ΔG°:  -38.1kJ/mole IC50: 650nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23251(4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid | LD...)
Affinity DataKi:  290nM ΔG°:  -37.3kJ/mole IC50: 140nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23242(3-hydroxy-1,2-oxazole-4-carboxylic acid | 1,2(1,5)...)
Affinity DataKi:  470nM ΔG°:  -36.1kJ/mole IC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed