Compile Data Set for Download or QSAR
Report error Found 13 of affinity data for UniProtKB/TrEMBL: Q24451
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84871(Swainsonine derivative, 6)
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84870(Swainsonine derivative, 5)
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84872(Swainsonine derivative, 7)
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84468(Mannostatin analogue, 4b | Meso-aminocyclopentitet...)
Affinity DataIC50: 1.00E+5nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84868(Swainsonine derivative, 3)
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84869(Swainsonine derivative, 4)
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84867(Swainsonine derivative, 2)
Affinity DataKi:  2.80nM ΔG°:  -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM50168995((-)-swainsonine | CHEMBL371197 | (1S,2R,8R,8aR)-Oc...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM50078117(Mannostatin A, 1 | (1R,2R,3R,4S,5R)-4-Amino-5-meth...)
Affinity DataKi:  36nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM50088625(Mannostatin analogue, 5 | CHEMBL427643 | (1R,2R,3R...)
Affinity DataKi:  76nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84614(Mannostatin B, 2)
Affinity DataKi:  150nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84615(Mannostatin analogue, 4a)
Affinity DataKi:  300nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM50088627(CHEMBL268037 | Mannostatin analogue, 3 | (1S,2S,3R...)
Affinity DataKi:  2.65E+5nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2012
Entry Details Article
PubMed