Compile Data Set for Download or QSAR
Report error Found 267 of affinity data for UniProtKB/TrEMBL: Q16850
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataKd:  69nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataKd:  26nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50280424(1-(4-Azido-phenyl)-2-imidazol-1-yl-ethanol | CHEMB...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity for cytochrome P450 14DMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50280425(1-(4-Azido-phenyl)-2-imidazol-1-yl-ethanone | CHEM...)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity for cytochrome P450 14DMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50280426(1-(4-Azido-benzyl)-1H-imidazole | CHEMBL447478)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity for cytochrome P450 14DMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50280427(1-(4-Azido-phenyl)-1H-imidazole | CHEMBL127685)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity for cytochrome P450 14DMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataKd:  7.00E+4nMAssay Description:Binding affinity to human CYP51More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataKd:  110nMAssay Description:Binding affinity to human CYP51More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataKd:  110nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human CYP51More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375211(CHEMBL535872)
Affinity DataKd:  340nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375212(CHEMBL558189)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375213(CHEMBL537002)
Affinity DataKd:  400nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375214(CHEMBL536772)
Affinity DataKd:  2.60E+5nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375215(CHEMBL538591)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375216(CHEMBL537231)
Affinity DataKd:  3.50E+4nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375217(CHEMBL537003)
Affinity DataKd:  2.92E+4nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50375218(CHEMBL557376)
Affinity DataKd:  2.70E+4nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataKd:  1.20E+5nMAssay Description:Binding affinity to human CYP51More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505758(CHEMBL4444489)
Affinity DataKd:  470nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505759(CHEMBL4593688)
Affinity DataKd:  1.15E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505760(CHEMBL4458275)
Affinity DataKd:  1.65E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505761(CHEMBL4277680)
Affinity DataKd:  60nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505763(CHEMBL4466288)
Affinity DataKd:  2.50E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505764(CHEMBL4461447)
Affinity DataKd:  20nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505765(CHEMBL4435160)
Affinity DataKd:  150nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505767(CHEMBL4472919)
Affinity DataKd:  2.32E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505768(CHEMBL4439225)
Affinity DataKd:  130nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50465948(CHEMBL3629567)
Affinity DataKd:  90nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505766(CHEMBL4522116)
Affinity DataKd:  90nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50505762(CHEMBL4452294)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to recombinant full length human CYP51 expressed in Escherichia coli incubated for 30 sec using [3H] labelled substrate by HPLC anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50215880(CHEMBL52311 | Ro-092364)
Affinity DataIC50: 22.5nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50215878(CHEMBL54768 | Ro-092056)
Affinity DataIC50: 28.1nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50215878(CHEMBL54768 | Ro-092056)
Affinity DataIC50: 28.1nMAssay Description:In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50215879(CHEMBL415943 | Ro-092435)
Affinity DataIC50: 56.3nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50215883(CHEMBL53214 | Ro-092182)
Affinity DataIC50: 73.3nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50215876(CHEMBL53213 | Ro-092173)
Affinity DataIC50: 83nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50011478(ITRAZOLE)
Affinity DataIC50: 85nMAssay Description:In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50215882(CHEMBL298394 | Ro-092183)
Affinity DataIC50: 86.8nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2018
Entry Details Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM50469749(CHEMBL349069 | Ro-092127)
Affinity DataIC50: 90.3nMAssay Description:In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628721(US20230339890, Compound 1)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628724(US20230339890, Compound 76)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628725(US20230339890, Compound 100)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628729(US20230339890, Compound 124)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628730(US20230339890, Compound 2)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628731(US20230339890, Compound 27)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628733(US20230339890, Compound 77)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

TargetLanosterol 14-alpha demethylase(Human)
Vanderbilt University

LigandPNGBDBM628735(US20230339890, Compound 125)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
Go to US Patent

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