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Report error Found 243 for UniProtKB: Q16654
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236533(CHEMBL316388)
Affinity DataEC50:  57nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472308(CHEMBL93045)
Affinity DataEC50:  5.40E+3nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM86249(ZD-6169 | ZD 6169)
Affinity DataEC50:  8.30E+3nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472314(CHEMBL421689)
Affinity DataEC50:  1.70E+4nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472313(CHEMBL310927)
Affinity DataEC50:  1.40E+3nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472318(CHEMBL304292)
Affinity DataEC50:  250nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177027(CPC-211 | Ceresine | DCA | Sodium dichloroacetate)
Affinity DataEC50:  1.30E+5nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472320(CHEMBL327693)
Affinity DataEC50:  590nMAssay Description:In vivo inhibion of pyruvate dehydrogenase kinase, increased oxidation of lactateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503708(CHEMBL4457385)
Affinity DataKd:  1.07E+4nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503709(CHEMBL4588123)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50525863(CHEMBL1708524)
Affinity DataEC50:  6.70E+4nMAssay Description:Inhibition of PDK4 (unknown origin) using PDCE1 as substrate incubated for 30 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50563139(CHEMBL4746836)
Affinity DataKd:  9.20E+3nMAssay Description:Binding affinity to PDK4 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526756(CHEMBL4591977)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472713(CHEMBL73068)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472668(CHEMBL74582)
Affinity DataIC50: 8nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526780(CHEMBL4551410)
Affinity DataIC50: 8nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472648(CHEMBL73204)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472670(CHEMBL75821)
Affinity DataIC50: 10nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526770(CHEMBL4519504)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50587504(CHEMBL5087040)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472647(CHEMBL73099)
Affinity DataIC50: 13nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526757(CHEMBL4575355)
Affinity DataIC50: 13nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472634(CHEMBL307687)
Affinity DataIC50: 15nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472654(CHEMBL75507)
Affinity DataIC50: 16nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472671(CHEMBL450618)
Affinity DataIC50: 16nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50236533(CHEMBL316388)
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory activity against Pyruvate dehydrogenase kinase by primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50587505(CHEMBL5072731)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472692(CHEMBL306972)
Affinity DataIC50: 19nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472676(CHEMBL72298)
Affinity DataIC50: 20nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472697(CHEMBL308151)
Affinity DataIC50: 20nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526772(CHEMBL4461160)
Affinity DataIC50: 20nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472310(CHEMBL84231)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity against Pyruvate dehydrogenase kinase by primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50236530(CHEMBL3727577)
Affinity DataIC50: 21nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472718(CHEMBL72567)
Affinity DataIC50: 23nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50587492(CHEMBL5079107)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472699(CHEMBL306835)
Affinity DataIC50: 29nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472637(CHEMBL73551)
Affinity DataIC50: 32nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50587493(CHEMBL5087238)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472674(CHEMBL72021)
Affinity DataIC50: 34nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526774(CHEMBL4540811)
Affinity DataIC50: 34nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472633(CHEMBL72204)
Affinity DataIC50: 35nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50587503(CHEMBL5089800)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472693(CHEMBL73100)
Affinity DataIC50: 47nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526773(CHEMBL4558944)
Affinity DataIC50: 52nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50526784(CHEMBL4558837)
Affinity DataIC50: 52nMAssay Description:Inhibition of PDHK4 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472314(CHEMBL421689)
Affinity DataIC50: 55nMAssay Description:In vitro inhibitory activity against Pyruvate dehydrogenase kinase by primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472635(CHEMBL74399)
Affinity DataIC50: 61nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Human)
Shaanxi Province Tuberculosis Prevention and Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50587494(CHEMBL5090085)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant PDHK4 co-complexed with porcine PDH using sodium pyruvate, coenzymeA and NAD as substrates preincubated with enzyme c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1,/2,/3,/4, mitochondrial(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472661(CHEMBL415267)
Affinity DataIC50: 66nMAssay Description:Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
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