Compile Data Set for Download or QSAR
Report error Found 268 of affinity data for UniProtKB/TrEMBL: Q16572
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50292902((2R,3R)-3-(4-(aminomethyl)-4-phenylpiperidin-1-yl)...)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018100(CHEMBL20721 | (+/-)-trans-2-hydroxy-3-(4-phenylpip...)
Affinity DataIC50: 10nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018100(CHEMBL20721 | (+/-)-trans-2-hydroxy-3-(4-phenylpip...)
Affinity DataIC50: 10nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183824(1-(2-bromobenzyl)-4-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018108(trans-(4S)-4-tert-butyl-2-(4-phenylpiperidin-1-yl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018094((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...)
Affinity DataIC50: 20nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50046947(CHEMBL172975)
Affinity DataIC50: 34nMAssay Description:Binding affinity to VAChTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018078(CHEMBL20943 | V-100 | 2-(4-Phenyl-piperidin-1-yl)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018117(CHEMBL21309 | 2-(4-Cyclohexyl-piperidin-1-yl)-cycl...)
Affinity DataIC50: 40nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183823(1-(3-bromobenzyl)-3-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183817(1-(2-bromobenzyl)-3-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018134(CHEMBL20499 | N-[6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018090(CHEMBL20382 | N-[6-Hydroxy-7-(4-phenyl-piperidin-1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018127(CHEMBL21271 | 1-[1-(2-Hydroxy-cyclohexyl)-4-phenyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018148(CHEMBL21151 | 3-(4-Phenyl-piperidin-1-yl)-1,2,3,4-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183813(1-benzyl-4-(4-phenylpiperazin-1-yl)piperidin-3-ol ...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183818(1-(3-bromobenzyl)-4-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018125(CHEMBL21243 | 2-[4-(3-Phenyl-propyl)-piperidin-1-y...)
Affinity DataIC50: 70nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018098(CHEMBL21722 | 5-tert-Butyl-2-(4-phenyl-piperidin-1...)
Affinity DataIC50: 90nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018080(CHEMBL20881 | 5-(2-Oxo-hexahydro-thieno[3,4-d]imid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018110(CHEMBL21165 | 2-[4-(4-Chloro-phenyl)-piperidin-1-y...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018079(CHEMBL277630 | 5-Amino-3-(4-phenyl-piperidin-1-yl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018115(CHEMBL281595 | 2-[4-(2,5-Dimethyl-phenyl)-piperazi...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018146(CHEMBL20481 | 2-(4-o-Tolyl-piperazin-1-yl)-cyclohe...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018135(CHEMBL282894 | 2-[4-(4-Nitro-phenyl)-piperidin-1-y...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018129(CHEMBL20479 | 3-(4-Phenyl-3,6-dihydro-2H-pyridin-1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018072(CHEMBL278303 | 3-(4-Phenyl-piperidin-1-yl)-cyclohe...)
Affinity DataIC50: 100nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183822(1-(2-methylallyl)-4-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183812(1-(4-bromobenzyl)-3-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183819(1-(2-methylallyl)-3-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183821(1-allyl-3-(4-phenylpiperazin-1-yl)piperidin-4-ol |...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183809(1-allyl-4-(4-phenylpiperazin-1-yl)piperidin-3-ol |...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183829(1-(4-bromobenzyl)-4-(4-phenylpiperazin-1-yl)piperi...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183816(3-(4-phenylpiperazin-1-yl)piperidin-4-ol | CHEMBL2...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183827((E)-1-(3-iodoallyl)-3-(4-phenylpiperazin-1-yl)pipe...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183826((E)-1-(but-2-enyl)-4-(4-phenylpiperazin-1-yl)piper...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183810(1-benzyl-3-(4-phenylpiperazin-1-yl)piperidin-4-ol ...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183825((E)-1-(3-iodoallyl)-4-(4-phenylpiperazin-1-yl)pipe...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183828(4-(4-phenylpiperazin-1-yl)piperidin-3-ol | CHEMBL3...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183820((E)-1-(but-2-enyl)-3-(4-phenylpiperazin-1-yl)piper...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50183814(3-(4-phenylpiperazin-1-yl)-1-(prop-2-ynyl)piperidi...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]vesamicol from human VAChT transfected in PC12 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018071(CHEMBL266183 | 5-(2-Oxo-hexahydro-thieno[3,4-d]imi...)
Affinity DataIC50: 200nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018076(CHEMBL277033 | 2-[4-(4-Chloro-phenyl)-3,6-dihydro-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018132(CHEMBL20720 | 2-(4-{3-[1-(2-hydroxycyclohexyl)hexa...)
Affinity DataIC50: 200nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018091(CHEMBL278834 | 2-(4-Phenyl-3,6-dihydro-2H-pyridin-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018092(CHEMBL20431 | 1-(2-Hydroxy-cyclohexyl)-4-phenyl-pi...)
Affinity DataIC50: 200nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018147(CHEMBL20429 | N-{4-[1-(2-Hydroxy-cyclohexyl)-piper...)
Affinity DataIC50: 200nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018085(CHEMBL21152 | (+/-)-trans-2-hydroxy-3-(4-(2-methox...)
Affinity DataIC50: 300nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50018106(CHEMBL283140 | 1-(4-Phenyl-piperidin-1-yl)-butan-2...)
Affinity DataIC50: 300nMAssay Description:Inhibition of active transport of [3H]acetylcholine using purified Torpedo californica synaptic vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 268 total ) | Next | Last >>
Jump to: