Compile Data Set for Download or QSAR
Report error Found 88 of affinity data for UniProtKB/TrEMBL: Q14534
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[(6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-amin...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032850([3-([3,3']Bithiophenyl-5-ylmethoxy)-benzyl]-((E)-6...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[(6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-amin...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032853(2-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 30nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032856(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032830({3-[(Dimethyl-o-tolyl-silanyl)-methoxy]-benzyl}-et...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032847(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032837(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of dog liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032848((6,6-Dimethyl-hepta-2,4-diynyl)-{3-[(dimethyl-o-to...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070344(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070337([3,3']Bithiophenyl-5-sulfonic acid [2-(3-{[((E)-6,...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032834(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50291660([3-([3,3']Bithiophenyl-5-ylmethoxy)-benzyl]-ethyl-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50288841((3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-ami...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032832(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032842({3-[(Benzyl-dimethyl-silanyl)-methoxy]-benzyl}-((E...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070341(Pyridine-3-sulfonic acid [2-(3-{[((E)-6,6-dimethyl...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032844(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032840(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(2-...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070345(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070343(Thiazole-2-sulfonic acid [2-(3-{[((E)-6,6-dimethyl...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070331(4-Cyano-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070350(N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethy...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070346([2,3']Bithiophenyl-5-sulfonic acid [2-(3-{[((E)-6,...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032835((3-{[(4-Bromo-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070342(Thiophene-2-sulfonic acid cyclopropyl-[2-(3-{[((E)...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070349(Thiophene-3-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070333(N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethy...)
Affinity DataIC50: 255nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50291661([3-(3-Azido-phenyl)-prop-2-ynyl]-[3-([3,3']bithiop...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070348(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-{3-[3-(t...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070339(4-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070347(4-Bromo-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070338(5-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50: 390nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032831((3-{[(4-Chloro-phenyl)-dimethyl-silanyl]-methoxy}-...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070335(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 450nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50291658((3-{[(4-Azido-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50: 520nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032851(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50: 870nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50291659([3-(4-Azido-phenyl)-prop-2-ynyl]-[3-([3,3']bithiop...)
Affinity DataIC50: 960nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032839(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032833(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070334(Benzo[b]thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032854(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50015507(CHEMBL47899 | 4,8,13,17,21-Pentamethyl-docosa-4,8,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50015503(CHEMBL416643 | 5,9,14,18,22-Pentamethyl-tricosa-5,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene monooxygenase(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032845(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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