Compile Data Set for Download or QSAR
Report error Found 8 of affinity data for UniProtKB/TrEMBL: Q14240
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 4.67E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50235738(Hippuristanol)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of eIF4G-induced eIF4A2 (unknown origin) RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) using single stranded poly(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50235737(CHEMBL4070102)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced eIF4A2 (unknown origin) RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) using single stranded poly(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50265561(CHEMBL4073833)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced human recombinant His6-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly(U) RNA as substrate after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50283445(CHEMBL4175313)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50283443(CHEMBL4170030)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetEukaryotic initiation factor 4A-II(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM65493(eIF4A3 inhibitor, 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A2 RNA dependent ATPase activity using single stranded poly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed