Compile Data Set for Download or QSAR
Report error Found 24 of affinity data for UniProtKB/TrEMBL: Q12974
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 48nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 48nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 52nMAssay Description:Inhibition of PTP4A2 (unknown origin) expressed in Escherichia coli assessed as reduction in hydrolysis using DIFMUP as substrate incubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM713966(US12202839, Compound 9o)
Affinity DataIC50: 73.9nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM713966(US12202839, Compound 9o)
Affinity DataIC50: 73.9nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM713962(US12202839, Compound 9k)
Affinity DataIC50: 113nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM713962(US12202839, Compound 9k)
Affinity DataIC50: 113nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 130nMAssay Description:Inhibition of human His6-tagged PRL-2 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 peptide as substrate by IMAP-FP as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM713969(US12202839, Compound 9p)
Affinity DataIC50: 264nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM713969(US12202839, Compound 9p)
Affinity DataIC50: 264nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 277nMAssay Description:Inhibition of human PRL2 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 substrate by immobilized metal ion affinity-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A2 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM45440(4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarbox...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP4A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50312665(Sodium 2-(2-Fluorophenyl)-6,7-methylenedioxyquinol...)
Affinity DataIC50: 314nMAssay Description:Inhibition of human PTP4A2 by enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black small volume microtiter plates, as previously described using r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
Go to US Patent

TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059140(CHEMBL3393148)
Affinity DataIC50: 3.14E+4nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059141(CHEMBL3393149)
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059086(CHEMBL3393146)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059142(CHEMBL3393150)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059143(CHEMBL3393151)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059085(CHEBI:8830 | Rhodanine)
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 2(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50059139(CHEMBL3393147)
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed