Compile Data Set for Download or QSAR
Report error Found 167 of affinity data for UniProtKB/TrEMBL: Q12888
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataKd:  2.20E+4nMpH: 8.0 T: 2°CAssay Description:All ITC measurements were recorded at 25 °C with an AutoITC200 microcalorimeter (MicroCal Inc.). All protein and compound stock samples were in the t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to 53BP1 methyllysine binding domain (unknown origin) by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50552663(CHEMBL4746871)
Affinity DataKd:  2.69E+3nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged lysine dye- labeled 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50552663(CHEMBL4746871)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 (DE3) cells by SPR a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630038(CHEMBL5403027)
Affinity DataKd:  790nMAssay Description:Binding affinity to N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) pLysS competent cells asse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630063(CHEMBL5439383)
Affinity DataKd:  170nMAssay Description:Binding affinity to N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) pLysS competent cells asse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630038(CHEMBL5403027)
Affinity DataKd:  850nMAssay Description:Binding affinity to N-terminal his6-tagged 53BP1 tandem tudor domain (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) pLysS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630063(CHEMBL5439383)
Affinity DataKd:  410nMAssay Description:Binding affinity to N-terminal his6-tagged 53BP1 tandem tudor domain (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) pLysS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630063(CHEMBL5439383)
Affinity DataIC50: 460nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630038(CHEMBL5403027)
Affinity DataIC50: 470nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630074(CHEMBL5402301)
Affinity DataIC50: 860nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630067(CHEMBL5431269)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630064(CHEMBL5433157)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50552663(CHEMBL4746871)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 (DE3) cells using Biotin-H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630052(CHEMBL5415556)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630069(CHEMBL5423332)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630062(CHEMBL5440895)
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440606(CHEMBL2426376)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630039(CHEMBL5421180)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630066(CHEMBL5430714)
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50552664(CHEMBL4740162)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged 53BP1 TTD (1484 to1603 residues) expressed in Escherichia coli BL21 (DE3) cells using Biotin-H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440602(CHEMBL2426479)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630068(CHEMBL5440393)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630042(CHEMBL5397384)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630070(CHEMBL5400477)
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630045(CHEMBL5397306)
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630046(CHEMBL5395836)
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630073(CHEMBL5428966)
Affinity DataIC50: 6.80E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630063(CHEMBL5439383)
Affinity DataIC50: 6.90E+3nMAssay Description:Antagonist activity at nanoluc-tagged 53BP1 tandem tudor domain (unknown origin) transfected in HEK293T cells assessed as inhibition of 53BP1-H4 pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440599(CHEMBL2426482)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630047(CHEMBL5429915)
Affinity DataIC50: 7.40E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630061(CHEMBL5412662)
Affinity DataIC50: 7.80E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440601(CHEMBL2426480)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630044(CHEMBL5418978)
Affinity DataIC50: 8.10E+3nMAssay Description:Displacement of Biotin-p53K381acK382me2 from N-terminal his6-tagged 53BP1 (1484 to 1603 residues) (unknown origin) expressed in Rosetta2 BL21 (DE3) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50630038(CHEMBL5403027)
Affinity DataIC50: 8.50E+3nMAssay Description:Antagonist activity at nanoluc-tagged 53BP1 tandem tudor domain (unknown origin) transfected in HEK293T cells assessed as inhibition of 53BP1-H4 pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440613(CHEMBL2426365)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440605(CHEMBL2424677)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440608(CHEMBL2426374)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440609(CHEMBL2426373)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440610(CHEMBL2426368)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440611(CHEMBL2426367)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440612(CHEMBL2426366)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440614(CHEMBL2426364)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440560(CHEMBL2426363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440561(CHEMBL2426362)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440562(CHEMBL2426361)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440564(CHEMBL2426359)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440565(CHEMBL2426358)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM50440566(CHEMBL2426478)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Displayed 1 to 50 (of 167 total ) | Next | Last >>
Jump to: