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TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551414(CHEMBL4779970)
Affinity DataEC50:  530nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50004821(SK-39315A | 2,3,4,5-Tetrahydro-1H-benzo[d]azepine-...)
Affinity DataEC50:  5.20E+3nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50230364(CHEMBL146629)
Affinity DataEC50: >1.00E+4nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551405(CHEMBL4784488)
Affinity DataEC50:  520nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551406(CHEMBL4740707)
Affinity DataEC50:  210nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551407(CHEMBL4786932)
Affinity DataEC50:  770nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551408(CHEMBL4761430)
Affinity DataEC50:  5.96E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551409(CHEMBL4789237)
Affinity DataEC50:  670nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551410(CHEMBL4760850)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551411(CHEMBL4759872)
Affinity DataEC50:  3.93E+4nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551412(CHEMBL4764988)
Affinity DataEC50:  430nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551413(CHEMBL4742351)
Affinity DataEC50:  3.53E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50:  71nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551415(CHEMBL4744648)
Affinity DataEC50:  310nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551416(CHEMBL4798759)
Affinity DataEC50:  5.05E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551417(CHEMBL4787822)
Affinity DataEC50:  2.48E+4nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551418(CHEMBL4760156)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551419(CHEMBL4751807)
Affinity DataEC50:  4.29E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551420(CHEMBL4745662)
Affinity DataEC50:  3.08E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551421(CHEMBL4747654)
Affinity DataEC50:  7.34E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551422(CHEMBL4761233)
Affinity DataEC50:  3.37E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551423(CHEMBL4795137)
Affinity DataEC50:  3.44E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551424(CHEMBL4754971)
Affinity DataEC50:  1.29E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551425(CHEMBL4761309)
Affinity DataEC50:  300nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551445(CHEMBL4782169)
Affinity DataEC50:  1.46E+4nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551444(CHEMBL4763908)
Affinity DataEC50:  960nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551443(CHEMBL4743444)
Affinity DataEC50:  1.08E+4nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551442(CHEMBL4800461)
Affinity DataEC50:  1.71E+4nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551441(CHEMBL4745593)
Affinity DataEC50:  750nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551440(CHEMBL4751176)
Affinity DataEC50:  1.64E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551439(CHEMBL4763027)
Affinity DataEC50:  6.81E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551438(CHEMBL4750740)
Affinity DataEC50:  170nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551437(CHEMBL4745564)
Affinity DataEC50:  3.23E+4nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551436(CHEMBL4754188)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551435(CHEMBL4794886)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551434(CHEMBL4799136)
Affinity DataEC50:  3.12E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551433(CHEMBL4800693)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551432(CHEMBL4758446)
Affinity DataEC50:  345nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551431(CHEMBL4762531)
Affinity DataEC50:  301nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551430(CHEMBL4781262)
Affinity DataEC50:  1.16E+4nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551429(CHEMBL4760543)
Affinity DataEC50:  1.08E+3nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551428(CHEMBL4744718)
Affinity DataEC50:  692nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551427(CHEMBL4777571)
Affinity DataEC50:  236nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50551426(CHEMBL4751732)
Affinity DataEC50:  90nMAssay Description:Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50634306(CHEMBL5403024)
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of human adenylate cyclase 2 expressed in ACdelta 3/6 knockout HEK293 cells assessed as cyclic AMP accumulation incubated for 30 min follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAdenylate cyclase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50010301(SKF 83566 | CHEMBL324017 | 8-Bromo-3-methyl-5-phen...)
Affinity DataIC50: 5.71E+3nMAssay Description:Inhibition of human adenylate cyclase 2 expressed in ACdelta 3/6 knockout HEK293 cells assessed as cyclic AMP accumulation incubated for 30 min follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50144001(3-{4-[1-(2',4'-Dichloro-biphenyl-4-ylcarbamoyl)-he...)
Affinity DataKi:  14nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50144020(3-{4-[1-(4-Benzofuran-2-yl-phenylcarbamoyl)-heptyl...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50144015(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-octyl]...)
Affinity DataKi:  20nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
University of Lund

Curated by ChEMBL
LigandPNGBDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  29nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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