Compile Data Set for Download or QSAR
Report error Found 2950 of affinity data for UniProtKB/TrEMBL: Q05397
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  1.20E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  64nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  440nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155525(US9012461, 1)
Affinity DataKd:  0.490nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155526(US9012461, 2)
Affinity DataKd:  1.5nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155527(US9012461, 3)
Affinity DataKd:  0.910nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155528(US9012461, 4)
Affinity DataKd:  0.730nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155529(US9012461, 7 | US9012461, 5)
Affinity DataKd:  0.570nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155530(US9012461, 6)
Affinity DataKd:  6.30nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155529(US9012461, 7 | US9012461, 5)
Affinity DataKd:  2.30nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155532(US9012461, 8)
Affinity DataKd:  1nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155533(US9012461, 9)
Affinity DataKd:  7nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
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Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155534(US9012461, 10)
Affinity DataKd:  0.960nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155535(US9012461, 11)
Affinity DataKd:  0.610nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155536(US9012461, 12)
Affinity DataKd:  0.920nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155537(US9012461, 13)
Affinity DataKd:  0.470nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155538(US9012461, 15 | US9012461, 14)
Affinity DataKd:  6.10nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155538(US9012461, 15 | US9012461, 14)
Affinity DataKd:  5nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155540(US9012461, 16)
Affinity DataKd:  1.30nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155541(US9012461, 17)
Affinity DataKd:  3.5nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155542(US9012461, 18)
Affinity DataKd:  13nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155543(US9012461, 19)
Affinity DataKd:  7.80nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155544(US9012461, 20)
Affinity DataKd:  0.630nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155545(US9012461, 21)
Affinity DataKd:  0.440nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155546(US9012461, 22)
Affinity DataKd:  0.990nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155547(US9012461, 23)
Affinity DataKd:  1.30nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155548(US9012461, 24)
Affinity DataKd:  0.770nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155549(US9012461, 25)
Affinity DataKd:  1.10nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155550(US9012461, 26)
Affinity DataKd:  14nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155551(US9012461, 27)
Affinity DataKd:  16.6nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155552(US9012461, 28)
Affinity DataKd:  0.940nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155553(US9012461, 29)
Affinity DataKd:  12.1nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155554(US9012461, 30)
Affinity DataKd:  5.70nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155555(US9012461, 31)
Affinity DataKd:  1nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155556(US9012461, 32)
Affinity DataKd:  2.5nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155557(US9012461, 33)
Affinity DataKd:  5.60nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155558(US9012461, 34)
Affinity DataKd:  5nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155559(US9012461, 35)
Affinity DataKd:  1.60nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM155560(US9012461, 36)
Affinity DataKd:  0.480nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50015561(Chlorpyramin HCl | CHLORPYRAMIN HYDROCHLORIDE)
Affinity DataKd:  570nMAssay Description:Binding affinity to biotinylated human FAK FAT domain by biolayer interoferometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50015562(CHEMBL3265344)
Affinity DataKd:  18nMAssay Description:Binding affinity to biotinylated human FAK FAT domain by biolayer interoferometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  68nMAssay Description:Average Binding Constant for PTK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for FAK kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding constant for FAK kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  210nMAssay Description:Binding constant for FAK kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  64nMAssay Description:Binding constant for FAK kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  64nMAssay Description:Binding constant for PTK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PTK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
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