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Report error Found 6 of affinity data for UniProtKB/TrEMBL: Q02111
TargetProtein kinase C theta type(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302040(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: 21nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302041(5-(5-((4-methoxypiperazin-1-yl)methyl)benzofuran-2...)
Affinity DataIC50: 360nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50: 590nMAssay Description:Inhibition of PKC-theta in mouse mixed lymphocyte reaction assessed as reduction in anti-CD3/CD28-stimulated IL-2 expression measured for 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetProtein kinase C theta type(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50239328(2-(3-((dimethylamino)methyl)phenyl)-4-(4-methyl-1H...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mouse PKCtheta in KO cells assessed as blockade of anti CD28-stimulated IL2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50573044(CHEMBL4873647)
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of PKC-theta in mouse whole blood assessed as reduction in anti-CD3/CD28-stimulated IL-2 expression measured for 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed