Compile Data Set for Download or QSAR
Report error Found 77 of affinity data for UniProtKB/TrEMBL: Q01279
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50182685(Canertinib dihydrochloride | CI-1033 | N-[4-(3-Chl...)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM112499(DACOMITINIB | US8623883, No. 2 | WO2022090481, Exa...)
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of wild type EGFR in mouse BaF3 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50038202(5-[(2,5-Dihydroxy-benzyl)-(2-hydroxy-benzyl)-amino...)
Affinity DataIC50: 11.5nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50025605(CHEMBL483830)
Affinity DataIC50: 27.7nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM3294(CHEMBL52765 | 4-N-(3-bromophenyl)quinazoline-4,6-d...)
Affinity DataIC50: 40nMAssay Description:Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50038199(5-(2,5-dihydroxybenzylamino)-2-hydroxybenzoic acid...)
Affinity DataIC50: 43.6nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50133373(N-(3-bromophenyl)-6-[(1E)-3-methyltriaz-1-enyl]qui...)
Affinity DataIC50: 70nMAssay Description:Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 81nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50136231(((2E)-3-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50136228(((2E)-3-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505838(CHEMBL4537790)
Affinity DataIC50: 190nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50133371(N-(3-methylphenyl)-6-[(1E)-3-methyltriaz-1-enyl]qu...)
Affinity DataIC50: 200nMAssay Description:Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505845(CHEMBL4566193)
Affinity DataIC50: 270nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50025591(CHEMBL483831)
Affinity DataIC50: 445nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50136230(6-[(1E)-3-acetyl-3-methyltriaz-1-enyl]-N-(3-methyl...)
Affinity DataIC50: 578nMAssay Description:Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505841(CHEMBL4532034 | US11174245, # I-018)
Affinity DataIC50: 700nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 750nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50102422(5-(2,5-dihydroxybenzylamino)-2-hydroxy-N-(3-phenyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505846(CHEMBL4562138)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505842(CHEMBL4519157)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50025606(LAVENDUSTIN B)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50619386(CHEMBL5424516)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of wild type EGFR in mouse BaF3 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50646289(CHEMBL5593705)
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505840(CHEMBL4550104)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50646287(CHEMBL5595541)
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50478479(CHEMBL520491)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of mouse EGFR by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074740(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505843(CHEMBL4449589 | US11174245, # I-235)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50102416(5-(2,5-Dihydroxy-benzylamino)-N-[2-(4-fluoro-pheny...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50102415(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(1,2,3,4...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505839(CHEMBL4525935 | US11174245, # I-001)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50102421(N-Benzyl-5-(2,5-dihydroxy-benzylamino)-2-hydroxy-b...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074742([3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-4-oxo-4H-...)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50162998(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50102423(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-phenethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50468244(CHEMBL4284413)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGFR in mouse BaF3 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50162991(3-(1-Benzo[b]thiophen-2-yl-1H-indol-3-yl)-4-[1-(3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50505836(CHEMBL4434788 | US11174245, # I-064)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGFR in mouse BAF3 cells assessed as reduction in cell proliferation incubated for 72 hrs by Celltiter-Glo luminescent cell v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50162994(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50162993(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50162996(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50162990(3-[1-(3-Dimethylamino-propyl)-1H-indazol-3-yl]-4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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