Compile Data Set for Download or QSAR
Report error Found 13 for UniProtKB: P9WG47
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50330327((R)-7-(3-(2-aminopropan-2-yl)pyrrolidin-1-yl)-9-cy...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50131428(CHEMBL32 | 1-Cyclopropyl-6-fluoro-8-methoxy-7-(oct...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50117914(1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpipera...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93038(Diospyrin)
Affinity DataIC50: 1.50E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50107009(5-Hydroxy-7-methyl-[1,4]naphthoquinone | 7-methylj...)
Affinity DataIC50: 3.00E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Csir-Central Institute of Medicinal and Aromatic Plants (Csir-Cimap)

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 as substrate after 30 mins by agarose gel electrophore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93039(Neodiospyrin)
Affinity DataIC50: 5.00E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50131445(CHEMBL33 | (S)-9-fluoro-3-methyl-10-(4-methylpiper...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93040(Isodiospyrin | MAR-UNI-c84db004-17)
Affinity DataIC50: 1.00E+5nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM24778(Vitamin K3 | cid_4055 | 2-methyl-1,4-dihydronaphth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93041(Shinanolone)
Affinity DataIC50: 2.00E+5nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMed