Compile Data Set for Download or QSAR
Report error Found 268 of affinity data for UniProtKB/TrEMBL: P97321
TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50636496(CHEMBL5557349)
Affinity DataKd: >700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM746820(US20250177582, Compound 28)
Affinity DataIC50: 0.00500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM746808(US20250177582, Compound 9)
Affinity DataIC50: 0.115nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700134(US20240335569, Compound 3BP-3621)
Affinity DataIC50: 0.630nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700141(US20240335569, Compound 3BP-3774)
Affinity DataIC50: 0.630nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700119(US20240335569, Compound 3BP-3233)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700129(US20240335569, Compound 3BP-3469)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700135(US20240335569, Compound 3BP-3622)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700702(US20240335569, Compound 3BP-3663)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700146(US20240335569, Compound 3BP-3951)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700109(US20240335569, Compound 3BP-3126)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700127(US20240335569, Compound 3BP-3467)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700128(US20240335569, Compound 3BP-3468)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700142(US20240335569, Compound 3BP-3785)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700143(US20240335569, Compound 3BP-3828)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700110(US20240335569, Compound 3BP-3127)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700136(US20240335569, Compound 3BP-3631)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700144(US20240335569, Compound 3BP-3829)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700148(US20240335569, Compound 3BP-3953)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700149(US20240335569, Compound 3BP-3954)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700151(US20240335569, Compound 3BP-4663)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700108(US20240335569, Compound 3BP-2929 | US20240382629, ...)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700133(US20240335569, Compound 3BP-3611)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700139(US20240335569, Compound 3BP-3772)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700147(US20240335569, Compound 3BP-3952)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700704(US20240335569, Compound 3BP-4026)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700154(US20240335569, Compound 3BP-4694)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700115(US20240335569, Compound 3BP-3205)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700132(US20240335569, Compound 3BP-3582)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700145(US20240335569, Compound 3BP-3830)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700703(US20240335569, Compound 3BP-4025)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700131(US20240335569, Compound 3BP-3581)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700706(US20240335569, Compound 3BP-4200)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700152(US20240335569, Compound 3BP-4664)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700150(US20240335569, Compound 3BP-4201)
Affinity DataIC50: 3.16nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700155(US20240335569, Compound 3BP-4808)
Affinity DataIC50: 3.16nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700156(US20240335569, Compound 3BP-4809)
Affinity DataIC50: 3.16nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 3.20nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50009364(CHEMBL3233840)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50009370(CHEMBL3233847)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700137(US20240335569, Compound 3BP-3632)
Affinity DataIC50: 3.98nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50009360(CHEMBL3233835 | US9346814, Cmpd No 23 Example 27)
Affinity DataIC50: 4.30nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50009360(CHEMBL3233835 | US9346814, Cmpd No 23 Example 27)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700126(US20240335569, Compound 3BP-3412)
Affinity DataIC50: 5.01nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50434163(CHEMBL2385273 | US9346814, Cmpd No 12 Example 15)
Affinity DataIC50: 6.20nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50434163(CHEMBL2385273 | US9346814, Cmpd No 12 Example 15)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM50434188(CHEMBL2385281 | US9346814, Cmpd No 2 Example 3 | U...)
Affinity DataIC50: 6.31nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

Curated by ChEMBL
LigandPNGBDBM700705(US20240335569, Compound 3BP-4197)
Affinity DataIC50: 6.31nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

Displayed 1 to 50 (of 268 total ) | Next | Last >>
Jump to: